LEADER 03277nam 22006735 450 001 9910298633503321 005 20200704022742.0 010 $a3-319-19189-6 024 7 $a10.1007/978-3-319-19189-8 035 $a(CKB)3710000000416747 035 $a(SSID)ssj0001500955 035 $a(PQKBManifestationID)11904646 035 $a(PQKBTitleCode)TC0001500955 035 $a(PQKBWorkID)11523064 035 $a(PQKB)11516697 035 $a(DE-He213)978-3-319-19189-8 035 $a(MiAaPQ)EBC6287207 035 $a(MiAaPQ)EBC5576395 035 $a(Au-PeEL)EBL5576395 035 $a(OCoLC)909779807 035 $a(PPN)186029497 035 $a(EXLCZ)993710000000416747 100 $a20150515d2015 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt 182 $cc 183 $acr 200 10$aProtein Ligation and Total Synthesis II /$fedited by Lei Liu 205 $a1st ed. 2015. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015. 215 $a1 online resource (VII, 229 p. 235 illus., 69 illus. in color.) 225 1 $aTopics in Current Chemistry,$x0340-1022 ;$v363 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a3-319-19188-8 327 $aHydroxyamine ketoacid ligation -- Chemical synthesis of proteins using N-sulfanylethylanilide peptides based on N-S acyl transfer chemistry -- Post ligation Desulfurization: A General Approach for Chemical Protein Synthesis -- Solid phase chemical synthesis of proteins -- New methods for protein chemical synthesis -- the chemical preparation of modified histones. 330 $a Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. 410 0$aTopics in Current Chemistry,$x0340-1022 ;$v363 606 $aBioorganic chemistry 606 $aProteins 606 $aPharmaceutical chemistry 606 $aBioorganic Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C19010 606 $aProtein Science$3https://scigraph.springernature.com/ontologies/product-market-codes/L14040 606 $aMedicinal Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C28000 615 0$aBioorganic chemistry. 615 0$aProteins. 615 0$aPharmaceutical chemistry. 615 14$aBioorganic Chemistry. 615 24$aProtein Science. 615 24$aMedicinal Chemistry. 676 $a574.19296 702 $aLiu$b Lei$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298633503321 996 $aProtein Ligation and Total Synthesis II$92050597 997 $aUNINA