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010   $a3-319-13584-8
024 7 $a10.1007/978-3-319-13584-7
035   $a(CKB)3710000000311694
035   $a(EBL)1968605
035   $a(OCoLC)908089889
035   $a(SSID)ssj0001408004
035   $a(PQKBManifestationID)11773986
035   $a(PQKBTitleCode)TC0001408004
035   $a(PQKBWorkID)11412381
035   $a(PQKB)11595587
035   $a(DE-He213)978-3-319-13584-7
035   $a(MiAaPQ)EBC1968605
035   $a(PPN)183154150
035   $a(EXLCZ)993710000000311694
100   $a20141203d2015      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aHolographic Sensors /$fby Ali Kemal Yetisen
205   $a1st ed. 2015.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015.
215   $a1 online resource (175 p.)
225 1 $aSpringer Theses, Recognizing Outstanding Ph.D. Research,$x2190-5053
300   $aDescription based upon print version of record.
311   $a3-319-13583-X 
320   $aIncludes bibliographical references.
327   $aIntroduction -- Materials and Methods -- pH-Responsive Holograms -- Divalent Metal Cation Selective Holographic Sensors -- Glucose-Responsive Holograms and Clinical Trials on Diabetic Patients -- A Smartphone Algorithm for the Quantification of Colorimetric Assays -- Final Discussion.
330   $aThis thesis presents a theoretical and experimental approach for the rapid fabrication, optimization and testing of holographic sensors for the quantification of pH, organic solvents, metal cations, and glucose in solutions. Developing non-invasive and reusable diagnostics sensors that can be easily manufactured will support the monitoring of high-risk individuals in any clinical or point-of-care setting. Sensor fabrication approaches outlined include silver-halide chemistry, laser ablation and photopolymerization. The sensors employ off-axis Bragg diffraction gratings of ordered silver nanoparticles and localized refractive index changes in poly (2-hydroxyethyl methacrylate) and polyacrylamide films. The sensors exhibited reversible Bragg peak shifts, and diffracted the spectrum of narrow-band light over the wavelength range ?peak ? 495-1100 nm. Clinical trials of glucose sensors in the urine samples of diabetic patients demonstrated that they offer superior performance compared to commercial high-throughput urinalysis devices. Lastly, a generic smartphone application to quantify colorimetric tests was developed and tested for both Android and iOS operating systems. The sensing platform and smartphone application may have implications for the development of low-cost, reusable and equipment-free point-of-care diagnostic devices.
410  0$aSpringer Theses, Recognizing Outstanding Ph.D. Research,$x2190-5053
606   $aChemical engineering
606   $aMedicinal chemistry
606   $aLaboratory medicine
606   $aIndustrial Chemistry/Chemical Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/C27000
606   $aMedicinal Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C28000
606   $aLaboratory Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B15007
615  0$aChemical engineering.
615  0$aMedicinal chemistry.
615  0$aLaboratory medicine.
615 14$aIndustrial Chemistry/Chemical Engineering.
615 24$aMedicinal Chemistry.
615 24$aLaboratory Medicine.
676   $a54
676   $a610724
676   $a615.19
676   $a660
700   $aYetisen$b Ali Kemal$4aut$4http://id.loc.gov/vocabulary/relators/aut$0991424
906   $aBOOK
912   $a9910298627303321
996   $aHolographic Sensors$92268939
997   $aUNINA