LEADER 04377nam 22008775 450 001 9910298613003321 005 20200630220803.0 010 $a3-319-14929-6 024 7 $a10.1007/978-3-319-14929-5 035 $a(CKB)3710000000399946 035 $a(EBL)2096942 035 $a(SSID)ssj0001500912 035 $a(PQKBManifestationID)11808236 035 $a(PQKBTitleCode)TC0001500912 035 $a(PQKBWorkID)11523512 035 $a(PQKB)10456982 035 $a(DE-He213)978-3-319-14929-5 035 $a(MiAaPQ)EBC2096942 035 $a(PPN)185490220 035 $a(EXLCZ)993710000000399946 100 $a20150413d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aAdvanced Time-Correlated Single Photon Counting Applications$b[electronic resource] /$fedited by Wolfgang Becker 205 $a1st ed. 2015. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015. 215 $a1 online resource (639 p.) 225 1 $aSpringer Series in Chemical Physics,$x0172-6218 ;$v111 300 $aDescription based upon print version of record. 311 $a3-319-14928-8 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aIntroduction into TCSPC -- Clinical and Preclinical Application of TCSPC -- Protein Structure and Protein Interaction -- NADH Dynamics -- Measurement of Local Environment Parameters in Biological Systems -- Oxygen Concentration Measurement in Biological tissue by Phosophorescence Lifetime Measurement. 330 $aThis book is an attempt to bridge the gap between the instrumental principles of multi-dimensional time-correlated single photon counting (TCSPC) and typical applications of the technique. Written by an originator of the technique and by sucessful users, it covers the basic principles of the technique, its interaction with optical imaging methods and its application to a wide range of experimental tasks in life sciences and clinical research. The book is recommended for all users of time-resolved detection techniques in biology, bio-chemistry, spectroscopy of live systems, live cell microscopy, clinical imaging, spectroscopy of single molecules, and other applications that require the detection of low-level light signals at single-photon sensitivity and picosecond time resolution. 410 0$aSpringer Series in Chemical Physics,$x0172-6218 ;$v111 606 $aPhysical chemistry 606 $aOptics 606 $aElectrodynamics 606 $aAtomic structure   606 $aMolecular structure  606 $aPhysical measurements 606 $aMeasurement    606 $aSignal processing 606 $aImage processing 606 $aSpeech processing systems 606 $aPhysical Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C21001 606 $aClassical Electrodynamics$3https://scigraph.springernature.com/ontologies/product-market-codes/P21070 606 $aAtomic/Molecular Structure and Spectra$3https://scigraph.springernature.com/ontologies/product-market-codes/P24017 606 $aMeasurement Science and Instrumentation$3https://scigraph.springernature.com/ontologies/product-market-codes/P31040 606 $aSignal, Image and Speech Processing$3https://scigraph.springernature.com/ontologies/product-market-codes/T24051 615 0$aPhysical chemistry. 615 0$aOptics. 615 0$aElectrodynamics. 615 0$aAtomic structure  . 615 0$aMolecular structure . 615 0$aPhysical measurements. 615 0$aMeasurement   . 615 0$aSignal processing. 615 0$aImage processing. 615 0$aSpeech processing systems. 615 14$aPhysical Chemistry. 615 24$aClassical Electrodynamics. 615 24$aAtomic/Molecular Structure and Spectra. 615 24$aMeasurement Science and Instrumentation. 615 24$aSignal, Image and Speech Processing. 676 $a539.7217 702 $aBecker$b Wolfgang$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298613003321 996 $aAdvanced Time-Correlated Single Photon Counting Applications$91939232 997 $aUNINA