LEADER 02947nam 2200601Ia 450 001 9910455495503321 005 20200520144314.0 010 $a0-585-09800-X 035 $a(CKB)111004365859988 035 $a(EBL)3039639 035 $a(SSID)ssj0000133783 035 $a(PQKBManifestationID)11145761 035 $a(PQKBTitleCode)TC0000133783 035 $a(PQKBWorkID)10053767 035 $a(PQKB)10920318 035 $a(MiAaPQ)EBC3039639 035 $a(Au-PeEL)EBL3039639 035 $a(CaPaEBR)ebr10605371 035 $a(OCoLC)923704498 035 $a(EXLCZ)99111004365859988 100 $a19950605d1994 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 04$aThe culture of violence$b[electronic resource] /$fedited by Kumar Rupesinghe and Marcial Rubio C 210 $aTokyo ;$aNew York $cUnited Nations University Press$dc1994 215 $a1 online resource (299 p.) 300 $aDescription based upon print version of record. 311 $a92-808-0866-4 320 $aIncludes bibliographical references. 327 $a""Contents""; ""Introduction 1""; ""Kumar Rupesinghe""; ""1 Forms of violence and its transformation 14""; ""Kumar Rupesinghe""; ""2 Rejoinder to the theory of structural violence 42""; ""Felipe E. MacGregor, S.J., and Marcial Rubio C.""; ""3 Remythologizations of power and identity: Nationalism and violence in Sri Lanka 59""; ""Bruce Kapferer""; ""4 The impact of drug trafficking on Colombian culture 92""; ""Francisco J. de Roux, S.J.""; ""5 Ethnic violence: The case of Bolivia 119""; ""Xavier AlbA?³""; ""6 Violence and conflict resolution in Uganda 144""; ""Edward Khiddu-Makubuya"" 327 $a""7 Violence and the welfare state: The case of Venezuela as an oil country 178""""Luis Pedro EspaA?ħa N.""; ""8 State terrorism and death squads in the New World Order 198""; ""Miles D. Wolpin""; ""9 Violence and culture in the United States 237""; ""Robert Brent Toplin""; ""10 Children in the city of violence: The case of Brazil 257""; ""Irene Rizzini""; ""11 Human rights and dictatorship: The case of Chile 276""; ""Tony Mifsud, S.J.""; ""Contributors 290"" 606 $aCivil war$xSocial aspects$vCase studies 606 $aPolitical violence$xSocial aspects$vCase studies 606 $aViolence$xCross-cultural studies$vCongresses 606 $aViolence$zLatin America$vCongresses 608 $aElectronic books. 615 0$aCivil war$xSocial aspects 615 0$aPolitical violence$xSocial aspects 615 0$aViolence$xCross-cultural studies 615 0$aViolence 701 $aRubio Correa$b Marcial$0949625 701 $aRupesinghe$b Kumar$0949626 712 02$aUnited Nations University. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910455495503321 996 $aThe culture of violence$92146425 997 $aUNINA LEADER 04468nam 22006855 450 001 9910298605103321 005 20250609110820.0 010 $a3-319-74920-X 024 7 $a10.1007/978-3-319-74920-4 035 $a(CKB)4100000002892365 035 $a(MiAaPQ)EBC5440577 035 $a(DE-He213)978-3-319-74920-4 035 $a(PPN)225548658 035 $a(MiAaPQ)EBC5589150 035 $a(EXLCZ)994100000002892365 100 $a20180315d2018 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMultifunctional Gold Nanostars for Cancer Theranostics /$fby Yang Liu 205 $a1st ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (83 pages) 225 1 $aSpringer Theses, Recognizing Outstanding Ph.D. Research,$x2190-5053 311 08$a3-319-74919-6 327 $aIntroduction -- Multifunctional GNS nanoprobe development and characterization -- In vivo evaluation of GNS nanoprobe -- GNS toxicity investigation -- Sensitive brain tumor detection using GNS nanoprobe -- Photoimmunotherapy for cancer metastasis treatment -- Conclusion and future outlook. 330 $aThis thesis presents the development of theranostic gold nanostars (GNS) for multimodality cancer imaging and therapy. Furthermore, it demonstrates that a novel two-pronged treatment, combining immune-checkpoint inhibition and GNS-mediated photothermal nanotherapy, can not only eradicate primary treated tumors but also trigger immune responses to treat distant untreated tumors in a mouse animal model. Cancer has become a significant threat to human health with more than eight million deaths each year, and novel methods for cancer management to improve patients? overall survival are urgently needed. The developed multifunctional GNS nanoprobe with tip-enhanced plasmonics in the near-infrared region can be combined with (1) surface-enhanced Raman spectroscopy (SERS), (2) two-photon photoluminescence (TPL), (3) X-ray computed tomography (CT), (4) magnetic resonance imaging (MRI), (5) positron emission tomography (PET), and (6) photothermal therapy (PTT) for cancer imaging and treatment. The ability of the GNS nanoprobe to detect submillimeter intracranial brain tumors was demonstrated using PET scan ? a superior non-invasive imaging modality ? in a mouse animal model. In addition, delayed rechallenge with repeated cancer cell injection in cured mice did not lead to new tumor formation, indicating generation of a memorized immune response to cancer. The biocompatible gold nanostars with superior capabilities for cancer imaging and treatment have great potential for translational medicine applications. 410 0$aSpringer Theses, Recognizing Outstanding Ph.D. Research,$x2190-5053 606 $aNanochemistry 606 $aCancer$xResearch 606 $aBiomaterials 606 $aSpectrum analysis 606 $aBiomedical engineering 606 $aPharmaceutical chemistry 606 $aNanochemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C33000 606 $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001 606 $aBiomaterials$3https://scigraph.springernature.com/ontologies/product-market-codes/Z13000 606 $aSpectroscopy/Spectrometry$3https://scigraph.springernature.com/ontologies/product-market-codes/C11020 606 $aBiomedical Engineering and Bioengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/T2700X 606 $aMedicinal Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C28000 615 0$aNanochemistry. 615 0$aCancer$xResearch. 615 0$aBiomaterials. 615 0$aSpectrum analysis. 615 0$aBiomedical engineering. 615 0$aPharmaceutical chemistry. 615 14$aNanochemistry. 615 24$aCancer Research. 615 24$aBiomaterials. 615 24$aSpectroscopy/Spectrometry. 615 24$aBiomedical Engineering and Bioengineering. 615 24$aMedicinal Chemistry. 676 $a616.99406 700 $aLiu$b Yang$4aut$4http://id.loc.gov/vocabulary/relators/aut$0651655 906 $aBOOK 912 $a9910298605103321 996 $aMultifunctional Gold Nanostars for Cancer Theranostics$91564864 997 $aUNINA