LEADER 13345nam 22007335 450 001 9910298598203321 005 20230822201635.0 010 $a3-319-28388-X 024 7 $a10.1007/978-3-319-28388-3 035 $a(CKB)3810000000358865 035 $a(DE-He213)978-3-319-28388-3 035 $a(MiAaPQ)EBC6314738 035 $a(PPN)229496601 035 $a(EXLCZ)993810000000358865 100 $a20180613d2018 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aModern Magnetic Resonance /$fedited by Graham A. Webb 205 $a2nd ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (742 illus., 481 illus. in color. eReference.) 311 $a3-319-28387-1 327 $aPART 1: Applications in Chemistry and Marine Sciences Foreword (by Gary Martin, Merck Research Laboratories) -- Amyloids -- Kinetics of Amyloid Fibril Formation of Human Calcitonin -- Polymorphism of Alzheimer?s Aß Amyloid Fibrils -- Chemical Shifts and Spin-Couplings -- 13C, 15N, 1H, 2H, and 17O NMR Chemical Shift NMR for Hydrogen Bonds -- NMR Chemical Shift Map -- NMR Chemical Shifts Based on Band Theory -- Modeling NMR Chemical Shifts -- Ab Initio Calculation of NMR Shielding Constants -- Crystal Structure Refinement Using Chemical Shifts -- The Theory of Nuclear Spin?Spin Couplings -- Fibrous Proteins -- Investigation of Collagen Dynamics by Solid-State NMR Spectroscopy -- Solid-State NMR Studies of Elastin and Elastin Peptides -- Structural Analysis of Silk Fibroins using NMR -- Field Gradient NMR -- NMR Diffusometry -- Field Gradient NMR of Liquid Crystals -- Field Gradient NMR for Polymer Systems with Cavities -- NMR Measurements Using Field Gradients and Spatial Information -- Theory and Application of NMR Diffusion Studies -- Host?Guest Chemistry -- Solid-State NMR in Host?Guest Chemistry -- Imaging -- Mapping of Flow and Acceleration with NMR Microscopy Techniques -- Industrial Application of In situ NMR Imaging Experiments to Steel-Making Process -- Biomedical NMR Spectroscopy and Imaging -- Electron Spin Resonance Imaging in Polymer Research -- NMR Imaging: Monitoring of Swelling of Environmental Sensitive Hydrogels -- Inorganic Materials and Catalysis -- Exploiting 1H to29Si Cross-Polarization Features for Structural Characterization of Inorganic Materials -- Solid State NMR Characterization of Solid Surface of Heterogeneous Catalysts -- Isotope Labeling -- Recent Developments in Stable-Isotope-Aided Methods for Protein NMR Spectroscopy -- Structural Glycobiology by Stable-isotope-assisted NMR Spectroscopy -- Lipid Bilayer and Bicelle -- Development and Application of Bicelles for Use in Biological NMR and Other Biophysical Studies -- Nuclear Magnetic Resonance of Oriented Bilayer Systems -- Solid-State Deuterium NMR Spectroscopy of Membranes -- Solid State 19F-NMR Analysis of Oriented Biomembranes -- Membrane-Associated Peptides -- Solid-State NMR Studies of the Interactions and Structure of Antimicrobial Peptides in Model Membranes -- Anisotropic Chemical Shift Perturbation Induced by Ions in Conducting Channels -- NMR Studies of Ion-Transporting Biological Channels -- Membrane Proteins -- Site-Directed NMR Studies on Membrane Proteins -- Structure of Membrane-Binding Proteins Revealed by Solid-State NMR -- Solid-State NMR of Membrane-Active Proteins and Peptides -- Magnetic Resonance Spectroscopic Studies of the Integral Membrane Protein Phospholamban -- NMR Studies of the Interactions Between Ligands and Membrane-Embedded -- Receptors: New Methods for Drug Discovery -- Photosynthetic Antennae and Reaction Centers -- Insight into Membrane Protein Structure from High-Resolution NMR -- New Developments -- Fast Multidimensional NMR: New Ways to Explore Evolution Space -- High-Sensitivity NMR Probe Systems -- CRAMPS -- Mobile NMR -- Rheo-NMR -- Analytical Aspects of Solid-State NMR Spectroscopy -- 3H NMR and Its Application -- On-line SEC?NMR -- NOE and Chemical Exchange -- The Nuclear Overhauser Effect -- Solute?Solvent Interactions Examined by the Nuclear Overhauser Effect -- Chemical Exchange -- NQR & ESR -- Separated Detection of H-Transfer Motions in Multi-H-Bonded Systems Studied by Combined 1H NMR and 35Cl NQR Measurements -- EPR: Principles -- Zero Field NMR: NMR and NQR in Zero Magnetic Field -- Organo Metallic Chemistry -- Organoboron Chemistry -- Organogermanium Chemistry -- Organotin Chemistry -- Paramagnetic Effects -- 1H and 13C High-Resolution Solid-State NMR of Paramagnetic Compounds Under Very Fast Magic Angle Spinning -- Paramagnetic Effects of Dioxygen in Solution NMR?Studies of Membrane Immersion Depth, Protein Topology, and Protein Interactions -- Protein Structure -- TROSY NMR for Studies of Large Biological Macromolecules in Solution -- NMR Insight of Structural Stability and Folding of Calcium-Binding Lysozyme -- NMR Investigation of Calmodulin -- Analytical Framework for Protein Structure Determination by Solid-State NMR of Aligned Samples -- Determining Protein 3D Structure by Magic Angle Spinning NMR -- 19F NMR Study of b-Type Haemoproteins -- Polymer Structure -- NMR in Dry or Swollen Temporary or Permanent Networks -- Crystalline Structure of Ethylene Copolymers and Its Relation to the Comonomer Content -- Isomorphism in Bacterially Synthesized Biodegradable Copolyesters -- Two-Dimensional NMR Analysis of Stereoregularity of Polymers -- Quantitative Analysis of Conformations in Disordered Polymers by Solid-State Multiple-Quantum NMR -- Polymer Microstructure: The Conformational Connection to NMR -- Solid-State NMR Characterization of Polymer Interfaces -- The Structure of Polymer Networks -- 1H CRAMPS NMR of Polypeptides in the Solid State -- Polymer Dynamics -- Dynamics of Amorphous Polymers -- Molecular Motions of Crystalline Polymers by Solid-State MAS NMR -- Dynamics in Polypeptides by Solid State 2H NMR -- Polymer Blends -- Polymer Blends -- Configurational Entropy and Polymer Miscibility: New Experimental Insights From Solid-State NMR -- Quantum Information Processing -- Quantum Information Processing as Studied by Molecule-Based Pulsed ENDOR Spectroscopy -- Residual Dipolar Couplings and Nucleic Acids -- New Applications for Residual Dipolar Couplings: Extending the Range of NMR in Structural Biology -- Refinement of Nucleic Acid Structures with Residual Dipolar Coupling Restraints in Cartesian Coordinate -- Conformational Analysis of DNA and RNA -- Solid-State NMR Technique -- Analytical and Numerical Tools for Experiment Design in Solid-State NMR Spectroscopy -- Homonuclear Shift-Correlation Experiment in Solids -- Two-Dimensional 17O Multiple-Quantum Magic-Angle Spinning NMR of Organic Solids -- A Family of PISEMA Experiments for Structural Studies of Biological Solids -- Structural Constraints in Solids -- Rotational-Echo, Double-Resonance NMR -- REDOR in Multiple Spin System -- Torsion Angle Determination by Solid-State NMR -- Secondary Structure Analysis of Proteins from Angle-Dependent Interactions -- Telomeric DNA Complexes -- Comparison of DNA-Binding Activities Between hTRF2 and hTRF1 with hTRF2 Mutants -- Optimization of MRI Contrast for Pre-Clinical Studies at High Magnetic Field -- The Application of In Vivo MRI and MRS in Phenomic Studies of Murine Models of Disease -- Experimental Models of Brain Disease: MRI Contrast Mechanisms for the Assessment of Pathophysiological Status -- Experimental Models of Brain Disease: MRI Studies -- Application of MRS in Cancer in Pre-clinical Models -- Experimental Cardiovascular MR in Small Animals -- Application of Pharmacological MRI to Preclinical Drug Discovery and Development -- Application of MRI to Cell Tracking -- Comprehensive Compositional Analysis of Fish Feed by Time Domain NMR -- Low Field NMR Studies of Atlantic Salmon (Salmo salar) -- Water Distribution and Mobility in Fish Products in Relation to Quality -- Proton NMR of Fish Oils and Lipids -- Determination of Fatty Acid Composition and Oxidation in Fish Oils by High Resolution Nuclear Magnetic Resonance Spectroscopy -- Resonance Spectroscopy to Study Lipid Oxidation in Fish and Fish Products -- Omega-3 Fatty Acid Content of Intact Muscle of Farmed Atlantic Salmon (Salmo salar) Examined by 1H MAS NMR Spectroscopy -- HR MAS NMR Spectroscopy of Marine Microalgae, Part 1: Classification and Metabolite Composition from HR MAS 1H NMR Spectra and Multivariate Analysis -- HR MAS NMR Spectroscopy of Marine Microalgae, Part 2: 13C and 13C HR MAS NMR Analysis Used to Study Fatty Acid Composition and Polysaccharide Structure -- Post-mortem Studies of Fish Using Magnetic Resonance Imaging -- How is the Fish Meat Affected by Technological Processes? PART 2: Applications in Biological and Pharmaceutical Sciences Foreword -- Acquiring Neurospectroscopy in Clinical Practice -- Application of Magnetic Resonance for the Diagnosis of Infective Brain Lesions -- Application of 2D Magnetic Resonance Spectroscopy to the Study of Human Biopsies -- Correlation of Histopathology with Magnetic Resonance Spectroscopy of Human Biopsies -- Functional MRI -- High Resolution Magic Angle Spinning (HRMAS) Proton MRS of Surgical Specimens -- Intraoperative MRI -- In Vivo Magnetic Resonance Spectroscopy in Breast Cancer -- In Vivo Molecular MR Imaging: Potential and Limits -- In vivo 13C MRS -- Magnetic Resonance Spectroscopy and Spectroscopic Imaging of the Prostate, Breast, and Liver -- MR-Mammography -- Phosphorus Magnetic Resonance Spectroscopy on Biopsy and In Vivo -- Radio Frequency Coils for Magnetic Resonance Spectroscopy -- Spatially Resolved Two-Dimensional MR Spectroscopy in vivo -- Overview of NMR in the Pharmaceutical Sciences -- Instrumentation -- Applications of Cryogenic NMR Probe Technology for the Identification of Low-Level Impurities in Pharmaceuticals -- Flow NMR Techniques in the Pharmaceutical Sciences -- Developments in NMR Hyphenation for Pharmaceutical Industry -- LC-NMR in Dereplication and Structure Elucidation of Herbal Drugs -- Techniques -- New Approaches to NMR Data Acquisition, Assignment and Protein Structure Determination: Potential Impact in Drug Discovery -- Transferred Cross-Correlated Relaxation: Application to Drug/Target Complexes -- Novel Uses of Paramagnets to Solve Complex Protein Structures -- Fast Assignments of 15N-HSQC Spectra of Proteins by Paramagnetic Labeling -- Phospholipid Bicelle Membrane Systems for Studying Drug Molecules -- Partial Alignment for Structure Determination of Organic Molecules -- Measurement of Residual Dipolar Couplings and Applications in Protein NMR -- Using Chemical Shift Perturbations to Validate and Refine the Docking of Novel IgE Antagonists to the High-Affinity IgE Receptor -- Du. 330 $aThis completely revised and updated second edition showcases the considerable progress that has taken place in this field since 2008. The three part reference work contains key developments, scores of contributions, key literature citations and overviews of the important progress achieved in the relevant topics since the publication of the previous edition. Two key differences in this new edition are the replacement of the previous Medical Sciences section with the Biological and Pharmaceutical Science sections and the inclusion of a new part featuring Archaeological applications. Divided into seven comprehensive parts, the work covers: Archaeology, Biological Sciences, Chemistry, Food Science, Marine Science, Materials Science, and Pharmaceutical Science. Section editors from Asia, USA, and Europe have recruited a truly international list of active and eminent contributors who have created a remarkable and unique work.  Topics include: Electron Spin Resonance, High resolution solid and liquid state NMR; Low resolution NMR; Solution State NMR; Magnetic Resonance Imaging. The level of scientific coverage of the chosen topics renders the handbook suitable for research workers in the relevant fields as well as final year undergraduate students. . 606 $aMaterials$xAnalysis 606 $aPharmaceutical chemistry 606 $aArchaeology 606 $aMedicine$xResearch 606 $aBiology$xResearch 606 $aFood science 606 $aWater 606 $aHydrology 606 $aCharacterization and Analytical Technique 606 $aPharmaceutics 606 $aArchaeology 606 $aBiomedical Research 606 $aFood Science 606 $aWater 615 0$aMaterials$xAnalysis. 615 0$aPharmaceutical chemistry. 615 0$aArchaeology. 615 0$aMedicine$xResearch. 615 0$aBiology$xResearch. 615 0$aFood science. 615 0$aWater. 615 0$aHydrology. 615 14$aCharacterization and Analytical Technique. 615 24$aPharmaceutics. 615 24$aArchaeology. 615 24$aBiomedical Research. 615 24$aFood Science. 615 24$aWater. 676 $a538.36 702 $aWebb$b Graham A$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298598203321 996 $aModern Magnetic Resonance$91566634 997 $aUNINA LEADER 07387nam 2200601Ia 450 001 9910438000203321 005 20200520144314.0 010 $a1-283-74048-6 010 $a1-4614-4304-0 024 7 $a10.1007/978-1-4614-4304-9 035 $a(CKB)2670000000278090 035 $a(EBL)1030419 035 $a(OCoLC)819379524 035 $a(SSID)ssj0000789880 035 $a(PQKBManifestationID)11413154 035 $a(PQKBTitleCode)TC0000789880 035 $a(PQKBWorkID)10735512 035 $a(PQKB)10733603 035 $a(DE-He213)978-1-4614-4304-9 035 $a(MiAaPQ)EBC1030419 035 $a(PPN)168299836 035 $a(EXLCZ)992670000000278090 100 $a20121108d2012 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 04$aThe brain-dead organ donor $epathophysiology and management /$fDimitri Novitzky, David K. C. Cooper, editors 205 $a1st ed. 2013. 210 $aNew York $cSpringer$d2012 215 $a1 online resource (368 p.) 300 $aDescription based upon print version of record. 311 $a1-4614-4303-2 320 $aIncludes bibliographical references and index. 327 $aIntroduction -- Historical Aspects of the Diagnosis of Death -- The Determination of Brain Death -- Legal Aspects of Declaration of Brain Death and Organ Donation.-Ethical Aspects of Declaration of Brain Death and Organ Donation -- Pathophysiology of Brain Death in Small Animal Models.-Pathophysiology of Brain Death and Effects of Hormonal Therapy in Large Animal Models.-The Efficacy of Thyroid Hormone Therapy in Brain-Dead Heart Donors: A Review of Thyroid Function in Health and Disease.-The Inflammatory Response to Brain Death -- The Influence of Brain Death and Intensive Care Management on Donor Organs: Assessment of Inflammatory Markers.-Brain-Death?Induced Inflammation: Possible Role of the Cholinergic Anti-Inflammatory Pathway -- Innate Immunity and Injury During Brain Death: Opportunities for Intervention -- Selection of the Brain-Dead Potential Organ Donor -- Infectious Disease Aspects of the Brain-Dead Potential Organ Donor -- Malignancy in the Brain-Dead Organ Donor -- Early Clinical Experience of Hormonal Therapy in the Brain-Dead Potential Organ Donor -- Assessment, Monitoring, and Management of the Brain-Dead Potential Organ Donor -- Assessment, Monitoring and Management of Brain-Dead Potential Organ Donors in Europe -- Current Management of Brain Dead Donors in Australia -- Management of the Brain-Dead Organ Donor?Perspectives of the Transplant Coordinator.-Surgical Aspects of Thoracic and Abdominal Organ Procurement from Brain-Dead Donors -- Impact of Brain Death on Storage of the Heart -- Impact of Brain Death on Abdominal Organs and Allograft Preservation Strategies -- Functional Repair of Brain Death-Induced Injury.-Functional Repair of Brain-Death-Injured Donor Lungs -- Thyroid Hormone Therapy to the Recipient of a Heart from a Brain-Dead Donor -- Current and Potential Future Trends in the Management of the Brain-Dead Organ Donor.-Maximizing Utilization of the Potential Deceased Donor?The Challenge Continues. Introduction -- Historical Aspects of the Diagnosis of Death -- The Determination of Brain Death -- Legal Aspects of Declaration of Brain Death and Organ Donation.-Ethical Aspects of Declaration of Brain Death and Organ Donation -- Pathophysiology of Brain Death in Small Animal Models.-Pathophysiology of Brain Death and Effects of Hormonal Therapy in Large Animal Models.-The Efficacy of Thyroid Hormone Therapy in Brain-Dead Heart Donors: A Review of Thyroid Function in Health and Disease.-The Inflammatory Response to Brain Death -- The Influence of Brain Death and Intensive Care Management on Donor Organs: Assessment of Inflammatory Markers.-Brain-Death?Induced Inflammation: Possible Role of the Cholinergic Anti-Inflammatory Pathway -- Innate Immunity and Injury During Brain Death: Opportunities for Intervention -- Selection of the Brain-Dead Potential Organ Donor -- Infectious Disease Aspects of the Brain-Dead Potential Organ Donor -- Malignancy in the Brain-Dead Organ Donor -- Early Clinical Experience of Hormonal Therapy in the Brain-Dead Potential Organ Donor -- Assessment, Monitoring, and Management of the Brain-Dead Potential Organ Donor -- Assessment, Monitoring and Management of Brain-Dead Potential Organ Donors in Europe -- Current Management of Brain Dead Donors in Australia -- Management of the Brain-Dead Organ Donor?Perspectives of the Transplant Coordinator.-Surgical Aspects of Thoracic and Abdominal Organ Procurement from Brain-Dead Donors -- Impact of Brain Death on Storage of the Heart -- Impact of Brain Death on Abdominal Organs and Allograft Preservation Strategies -- Functional Repair of Brain Death-Induced Injury.-Functional Repair of Brain-Death-Injured Donor Lungs -- Thyroid Hormone Therapy to the Recipient of a Heart from a Brain-Dead Donor -- Current and Potential Future Trends in the Management of the Brain-Dead Organ Donor.-Maximizing Utilization of the Potential Deceased Donor?The Challenge Continues. 330 $aAddressing all aspects of brain death and thoroughly detailing how a potential organ donor should be maintained to ensure maximum use of the organs and cells, The Brain-Dead Organ Donor: Pathophysiology and Management is a landmark addition to the literature.  This first-of-its-kind, multidisciplinary volume will be of interest to a large section of the medical community. The first section of the book reviews the historical, medical, legal, and ethical aspects of brain death.  That is followed by two chapters on the pathophysiology of brain death as investigated in small and large animal models.  This includes a review of the many hormonal changes, including the neuroendocrine- adrenergic ?storm?, that takes place during and following the induction of brain death, and how they impact metabolism.  The next section of the book reviews various effects of brain death, namely its impact on thyroid function, the inflammatory response that develops, and  those relating to innate immunity. The chapters relating to assessment and management of potential organ donors will be of interest to a very large group of transplant surgeons and physicians as well as critical care and neurocritical care physicians and nurses. Neurologists, endocrinologists, neurosurgeons, and pathologists will also be interested, especially in the more basic science sections on various aspects of brain-death and hormonal therapy. Organ procurement organizations and transplant coordinators worldwide will also be interested in this title. Other chapters will be of interest to medical historians, medico-legal experts, and ethicists.  . 606 $aDonation of organs, tissues, etc 606 $aBrain death 606 $aTransplantation of organs, tissues, etc 615 0$aDonation of organs, tissues, etc. 615 0$aBrain death. 615 0$aTransplantation of organs, tissues, etc. 676 $a617.954 701 $aNovitzky$b Dimitri$01752341 701 $aCooper$b D. K. C$g(David K. C.),$f1939-$01631952 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910438000203321 996 $aThe brain-dead organ donor$94187613 997 $aUNINA