LEADER 04334nam 22006255 450 001 9910298597003321 005 20231128212549.0 010 $a3-319-61590-4 024 7 $a10.1007/978-3-319-61590-5 035 $a(CKB)4340000000223248 035 $a(DE-He213)978-3-319-61590-5 035 $a(MiAaPQ)EBC6314306 035 $a(MiAaPQ)EBC5579496 035 $a(Au-PeEL)EBL5579496 035 $a(OCoLC)1066191563 035 $a(PPN)221254285 035 $a(EXLCZ)994340000000223248 100 $a20171127d2018 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBiotransformations in organic chemistry $ea textbook /$fby Kurt Faber 205 $a7th ed. 2018 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018 215 $a1 online resource (XI, 434 p. 327 illus., 314 illus. in color.) 311 $a3-319-61589-0 327 $aIntroduction -- Common Prejudices Against Enzymes -- Advantages and Disadvantages of Biocatalysts. Enzyme Properties and Nomenclature -- Biocatalytic Applications: Hydrolytic Reactions -- Reduction Reactions -- Oxidation Reactions -- Formation of Carbon-Carbon Bonds -- Addition and Elimination Reactions -- Transfer Reactions -- Halogenation and Dehalogenation Reactions -- Special Techniques: Enzymes in Organic Solvents -- Cascade Reactions -- Immobilization -- Artificial and Modified Enzymes -- State of the Art and Outlook -- Appendix: Basic Rules for Handling Biocatalysts -- Abbreviations -- Suppliers of Enzymes -- Commonly Used Enzyme Preparations -- Major Culture Collections -- Pathogenic Bacteria and Fungi -- Index 330 $aThis well-established textbook on biocatalysis provides a basis for undergraduate and graduate courses in modern organic chemistry, as well as a condensed introduction into this field. After a basic introduction into the use of biocatalysts?principles of stereoselective transformations, enzyme properties and kinetics?the different types of reactions are explained according to the 'reaction principle', such as hydrolysis, reduction, oxidation, C?C bond formation, etc. Special techniques, such as the use of enzymes in organic solvents, immobilization techniques, artificial enzymes and the design of cascade-reactions are treated in a separate section. A final chapter deals with the basic rules for the safe and practical handling of biocatalysts. The use of biocatalysts, employed either as isolated enzymes or whole microbial cells, offers a remarkable arsenal of highly selective transformations for state-of-the-art synthetic organic chemistry. Over the last two decades, this methodology has become an indispensable tool for asymmetric synthesis, not only at the academic level, but also on an industrial scale. In this 7th edition new topics have been introduced which include alcohol and amine oxidases, amine dehydrogenases, imine reductases, haloalkane dehalogenases, ATP-independent phosphorylation, Michael-additions and cascade reactions. This new edition also emphasizes the use of enzymes in industrial biotransformations with practical examples 606 $aChemistry, Organic 606 $aBiotechnology 606 $aBiochemistry 606 $aGreen chemistry 606 $aOrganic Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C19007 606 $aBiotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/C12002 606 $aBiochemistry, general$3https://scigraph.springernature.com/ontologies/product-market-codes/L14005 606 $aGreen Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C35000 615 0$aChemistry, Organic. 615 0$aBiotechnology. 615 0$aBiochemistry. 615 0$aGreen chemistry. 615 14$aOrganic Chemistry. 615 24$aBiotechnology. 615 24$aBiochemistry, general. 615 24$aGreen Chemistry. 676 $a660.634 700 $aFaber$b Kurt$4aut$4http://id.loc.gov/vocabulary/relators/aut$0282956 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298597003321 996 $aBiotransformations in organic chemistry$9884803 997 $aUNINA