LEADER 03792nam 22005895 450 001 9910298596403321 005 20200630173413.0 010 $a3-319-70839-2 024 7 $a10.1007/978-3-319-70839-3 035 $a(CKB)3850000000032868 035 $a(MiAaPQ)EBC5448941 035 $a(DE-He213)978-3-319-70839-3 035 $a(PPN)229501397 035 $a(EXLCZ)993850000000032868 100 $a20180705d2018 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAntibacterials $eVolume II /$fedited by Jed F. Fisher, Shahriar Mobashery, Marvin J. Miller 205 $a1st ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (222 pages) $cillustrations 225 1 $aTopics in Medicinal Chemistry,$x1862-2461 ;$v26 311 $a3-319-70838-4 327 $aNucleoside Natural Product Antibiotics Targetting Microbial Cell Wall Biosynthesis -- The Cyclic Lipopeptide Antibiotics -- Fully Synthetic Tetracyclines: Increasing Chemical Diversity to Combat Multidrug-Resistant Bacterial Infections -- The Antifolates -- The Oxazolidinones.- Sideromycins as Pathogen-Targeted Antibiotics -- Quorum Sensing Inhibitors as Pathoblockers for Pseudomonas aeruginosa Infections: A New Concept in Anti-Infective Drug Discovery. 330 $aMedicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors. 410 0$aTopics in Medicinal Chemistry,$x1862-2461 ;$v26 606 $aMedicinal chemistry 606 $aBiochemistry 606 $aOrganic chemistry 606 $aMedicinal Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C28000 606 $aBiochemistry, general$3https://scigraph.springernature.com/ontologies/product-market-codes/L14005 606 $aOrganic Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C19007 615 0$aMedicinal chemistry. 615 0$aBiochemistry. 615 0$aOrganic chemistry. 615 14$aMedicinal Chemistry. 615 24$aBiochemistry, general. 615 24$aOrganic Chemistry. 676 $a616.92061 702 $aFisher$b Jed F$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aMobashery$b Shahriar$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aMiller$b Marvin J$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298596403321 996 $aAntibacterials$91566645 997 $aUNINA