LEADER 05179nam 22006735 450 001 9910298456403321 005 20200630180043.0 010 $a3-319-20669-9 024 7 $a10.1007/978-3-319-20669-1 035 $a(CKB)3710000000501008 035 $a(EBL)4088843 035 $a(SSID)ssj0001583833 035 $a(PQKBManifestationID)16263612 035 $a(PQKBTitleCode)TC0001583833 035 $a(PQKBWorkID)14865445 035 $a(PQKB)11048975 035 $a(DE-He213)978-3-319-20669-1 035 $a(MiAaPQ)EBC4088843 035 $a(PPN)190518200 035 $a(EXLCZ)993710000000501008 100 $a20151102d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aInfection and Cancer: Bi-Directorial Interactions /$fedited by Michael R. Shurin, Yasmin Thanavala, Nahed Ismail 205 $a1st ed. 2015. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015. 215 $a1 online resource (400 p.) 300 $aDescription based upon print version of record. 311 $a3-319-20668-0 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aInfection and Cancer: Multi-directorial relationship -- Part I Infection-associated cancers -- Human tumor viruses: A historical perspective -- Epidemiology of virus infection and human cancer -- Bacterial infections and cancer development -- Human protozoal infections and their potential for causing neoplasms -- An update on helminths in human carcinogenesis -- Infection-associated hematological malignancies -- Multiple infections and cancer: Etiology, mechanisms and implications in cancer control -- Inflammatory mechanisms of infection-associated cancer -- Part II Infection-associated cancers: Specific examples -- Helicobacter pylori: The cancer bug -- Oral infection, carcinogenesis and cancer -- Streptococcus Bovis and colorectal cancer -- Human papillomavirus-related cancers -- Part III Cancer-associated infections -- Infectious diseases in cancer patients: An overview -- Part IV Infection and cancer: Comorbid development -- Comorbid development of infection and cancer -- Part V Infection agent-based vectors for cancer therapy -- Bacterial cancer therapy: how patients might benefit from Salmonella infections -- Development of Salmonella-based cancer vaccines -- Harnessing the host immune response to infection - BCG immunotherapy for bladder cancer -- Index. 330 $aThis unique book summarizes current knowledge on co-development of infectious diseases and cancer. It provides an overview of the complex and unique role of the immune system, inflammation, tumor-mediated immunosuppression and infection-induced immunomodulation in cancer and infection progression.   Chapters are organized into themed parts, beginning with a look at the historical perspective of human tumor viruses, then aspects and examples of infection-related cancers and cancer-associated infections. The work discusses how cancer- and infection-associated immune responses interact in a bi-directorial fashion and how these interactions may evolve during both disease progression and in response to therapy. The phenomenon of independent development of cancer and infection in the same host, known as comorbid cancer-infection progression, is explored.   Understanding the complex pathways involved in the progression of infection and cancer will allow the prevention of the development of certain types of cancer, as well as advancing prophylactic anti-cancer vaccines. Readers of this work will discover innovative approaches for multidisciplinary projects, focusing on the design of original therapeutic modalities for cancer therapy. The book will therefore be particularly valuable to scholars interested in cancer immunology and researchers and clinicians in the field of basic and applied immunobiology and microbiology.  . 606 $aCancer research 606 $aInfectious diseases 606 $aImmunology 606 $aMicrobiology 606 $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001 606 $aInfectious Diseases$3https://scigraph.springernature.com/ontologies/product-market-codes/H33096 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aMicrobiology$3https://scigraph.springernature.com/ontologies/product-market-codes/L23004 615 0$aCancer research. 615 0$aInfectious diseases. 615 0$aImmunology. 615 0$aMicrobiology. 615 14$aCancer Research. 615 24$aInfectious Diseases. 615 24$aImmunology. 615 24$aMicrobiology. 676 $a610 702 $aShurin$b Michael R$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aThanavala$b Yasmin$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aIsmail$b Nahed$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298456403321 996 $aInfection and Cancer: Bi-Directorial Interactions$92523500 997 $aUNINA