LEADER 04503nam 22007215 450 001 9910298453903321 005 20200705010510.0 010 $a3-319-16682-4 024 7 $a10.1007/978-3-319-16682-7 035 $a(CKB)3710000000434401 035 $a(EBL)2094646 035 $a(SSID)ssj0001525002 035 $a(PQKBManifestationID)11869187 035 $a(PQKBTitleCode)TC0001525002 035 $a(PQKBWorkID)11496959 035 $a(PQKB)10941709 035 $a(DE-He213)978-3-319-16682-7 035 $a(MiAaPQ)EBC2094646 035 $a(PPN)186395396 035 $a(EXLCZ)993710000000434401 100 $a20150620d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aMitochondrial Function In Vivo Evaluated by NADH Fluorescence$b[electronic resource] /$fby Avraham Mayevsky 205 $a1st ed. 2015. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015. 215 $a1 online resource (285 p.) 300 $aDescription based upon print version of record. 311 $a3-319-16681-6 320 $aIncludes bibliographical references and index. 327 $a1. Introduction -- 2. Tissue Energy Metabolism and Mitochondrial Function -- 3. Spectroscopic monitoring of NADH ? Historical Overview -- 4. Technological aspects of NADH monitoring In Vivo -- 5. Monitoring of NADH together with other tissue physiological parameters -- 6. Multisite Monitoring of NADH -- 7. Responses of NADH to physiological and pathophysiological conditions -- 8. Monitoring of various organs in various animal models -- 9. Monitoring of NADH in Human brain and body organs -- 10. Discussion -- Index. 330 $aThis book covers both the technological development and biomedical applications of NADH fluorescence. Topics covered include perspectives on the history of monitoring NADH fluorescence, the relationship between mitochondrial function and other functions at the tissue level, responses of NADH to physiological and pathophysiological conditions, monitoring of NADH in the human brain and other organs, and metabolism. It also includes an in-depth look at flavoprotein (Fp) fluorescence and NADH in relation to redox state. This is an ideal book for biomedical engineers, researchers, and graduate students interested in learning the biomedical applications of NADH fluorescence. This book also: Covers multisite monitoring of NADH, as well as multiparametric responses of NADH to physiological and pathophysiological conditions, and monitoring of various organs in various animal models Describes the relationship between brain activation (i.e. epileptic activity and cortical spreading depression) and NADH redox state Presents the effects of hypoxia, hyperbaric hyperoxia, and ischemia on brain NADH fluorescence and other tissue physiological parameters    About the Author Avraham Mayevsky, Ph.D. is a Professor Emeritus in the Faculty of Life Sciences and the Brain Research Center at Bar Ilan University, Israel. He has published  more than two hundred papers in the field of mitochondrial function and tissue physiology in vivo under pathophysiological conditions. 606 $aCell physiology 606 $aLasers 606 $aPhotonics 606 $aBiochemistry 606 $aMedical biochemistry 606 $aCell Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/L33010 606 $aOptics, Lasers, Photonics, Optical Devices$3https://scigraph.springernature.com/ontologies/product-market-codes/P31030 606 $aBiochemistry, general$3https://scigraph.springernature.com/ontologies/product-market-codes/L14005 606 $aMedical Biochemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/H35005 615 0$aCell physiology. 615 0$aLasers. 615 0$aPhotonics. 615 0$aBiochemistry. 615 0$aMedical biochemistry. 615 14$aCell Physiology. 615 24$aOptics, Lasers, Photonics, Optical Devices. 615 24$aBiochemistry, general. 615 24$aMedical Biochemistry. 676 $a570 676 $a571.6 676 $a572 676 $a612015 676 $a621.36 700 $aMayevsky$b Avraham$4aut$4http://id.loc.gov/vocabulary/relators/aut$01064292 906 $aBOOK 912 $a9910298453903321 996 $aMitochondrial Function In Vivo Evaluated by NADH Fluorescence$92537316 997 $aUNINA