LEADER 04829nam 22008055 450 001 9910298451703321 005 20230712195615.0 010 $a3-319-22671-1 024 7 $a10.1007/978-3-319-22671-2 035 $a(CKB)3710000000532685 035 $a(EBL)4189313 035 $a(SSID)ssj0001596881 035 $a(PQKBManifestationID)16297556 035 $a(PQKBTitleCode)TC0001596881 035 $a(PQKBWorkID)14886204 035 $a(PQKB)11150991 035 $a(DE-He213)978-3-319-22671-2 035 $a(MiAaPQ)EBC4189313 035 $a(PPN)190885343 035 $a(EXLCZ)993710000000532685 100 $a20151211d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$amicroRNA: Medical Evidence $eFrom Molecular Biology to Clinical Practice /$fedited by Gaetano Santulli 205 $a1st ed. 2015. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015. 215 $a1 online resource (428 p.) 225 1 $aAdvances in Experimental Medicine and Biology,$x2214-8019 ;$v888 300 $aDescription based upon print version of record. 311 $a3-319-22670-3 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $a -- 1) microRNA and personalized medicine -- 2) microRNA and chronic pain -- 3) microRNA and multiple sclerosis -- 4) microRNA and epilepsy  -- 5) microRNA and autism -- 6) microRNAs and fragile X syndrome -- 7) microRNAs and neurodegenerative disorders -- 8) microRNA and metabolism: focus on mitochondria -- 9) microRNA in cerebrovascular diseases   -- 10)  microRNA and cardiac regeneration -- 11)  microRNA and arterial -- 12)  microRNA and pulmonary hypertension . - 13) microRNA and diabetic kidney disease -- 14)  MicroRNA and kidney transplantation -- 15) microRNA and wound healing -- 16) microRNA in dermatology -- 17) microRNA and allergy -- 18) Endometriosis -- 19) microRNA role in human -- 20) microRNA and hepatitis B -- 21) BIO microRNA and aging -- 22) microRNA and doping -- 23) microRNA profiling. 330 $aThis volume explores microRNA function in a wide array of human disorders, providing a clinical basis for precision medicine and personalized therapies using these molecules. The twenty-one chapters, all authored by internationally-renowned experts, open with an introduction contextualizing microRNA manipulation within today?s initiatives towards precision medicine. The following chapters explore the clinical role of microRNAs in the diagnosis and treatment of metabolic and cardiovascular disorders, focusing on mitochondrial fitness, arterial hypertension, cardiovascular remodeling, cerebrovascular disease, pulmonary hypertension, diabetic kidney disease, and kidney transplantation. The subsequent chapters discuss the importance of microRNAs in the wound healing process and in skin disease, in the pathogenesis of allergy, in human ovulation, and in infection. The book concludes with chapters  which outline the emerging role of microRNAS in doping and detail microRNA profiling. microRNA: Medical Evidence is an ideal companion to both microRNA: Basic Science and microRNA: Cancer. Taken together, these three books provide a state-of-the-art overview of this rapidly-expanding and fascinating field, from the molecular level to clinical practice. It will be invaluable to medical students, physicians, and researchers, as a complete and unique guide in the exploration of microRNA in basic science, cancer and clinical practice. 410 0$aAdvances in Experimental Medicine and Biology,$x2214-8019 ;$v888 606 $aMedicine?Research 606 $aBiology?Research 606 $aCytology 606 $aAtomic structure  606 $aMolecular structure 606 $aBiochemistry 606 $aHuman physiology 606 $aBiomedical Research 606 $aCell Biology 606 $aAtomic and Molecular Structure and Properties 606 $aChemical Biology 606 $aHuman Physiology 615 0$aMedicine?Research. 615 0$aBiology?Research. 615 0$aCytology. 615 0$aAtomic structure . 615 0$aMolecular structure. 615 0$aBiochemistry. 615 0$aHuman physiology. 615 14$aBiomedical Research. 615 24$aCell Biology. 615 24$aAtomic and Molecular Structure and Properties. 615 24$aChemical Biology. 615 24$aHuman Physiology. 676 $a572.88 702 $aSantulli$b Gaetano$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298451703321 996 $aMicroRNA: Medical Evidence$92537534 997 $aUNINA