LEADER 03548nam 22007335 450 001 9910298443603321 005 20251113204918.0 010 $a94-017-7405-6 024 7 $a10.1007/978-94-017-7405-5 035 $a(CKB)3710000000492580 035 $a(EBL)4179199 035 $a(SSID)ssj0001583794 035 $a(PQKBManifestationID)16263990 035 $a(PQKBTitleCode)TC0001583794 035 $a(PQKBWorkID)14864922 035 $a(PQKB)10620318 035 $a(DE-He213)978-94-017-7405-5 035 $a(MiAaPQ)EBC4179199 035 $a(PPN)190524944 035 $a(EXLCZ)993710000000492580 100 $a20151014d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aDendritic Cells: Biophysics, Tumor Microenvironment and Chinese Traditional Medicine /$fby Zhu Zeng, Xiaofeng Xu, Dan Chen 205 $a1st ed. 2015. 210 1$aDordrecht :$cSpringer Netherlands :$cImprint: Springer,$d2015. 215 $a1 online resource (70 p.) 225 1 $aSpringerBriefs in Biochemistry and Molecular Biology,$x2211-9361 300 $aDescription based upon print version of record. 311 08$a94-017-7403-X 320 $aIncludes bibliographical references. 327 $aSummary -- Introduction.- The measurement protocols of cell biophysical characteristics -- Biophysical characteristics of dendritic cells at different differentiation stages -- Biophysical characteristics of dendritic cells in tumor microenvironment -- Effects of Chinese traditional herbs on dendritic cells -- Future perspectives. 330 $aIn this book, the authors discuss the biophysical characteristics of Dendritic cells (DCs) at various differentiation stages and in tumor microenvironments in detail. A type of Chinese traditional herb, which can improve the biophysical and microrheological properties of DCs, is also introduced. DCs are potent and specialized antigen-presenting cells that play a crucial role in initiating and amplifying both the innate and adaptive immune responses. The biophysical and microrheological characteristics of DCs are important for their motility and normal immune function. In tumor microenvironments, the motility and immune functions of DCs are impaired, but the mechanisms are largely unknown. This book offers researchers a comprehensive and deep insight into the biophysical characteristics of DCs and may also help to improve the efficiency of anti-tumor therapy based on DCs.     . 410 0$aSpringerBriefs in Biochemistry and Molecular Biology,$x2211-9361 606 $aImmunology 606 $aBiophysics 606 $aCancer 606 $aPharmacology 606 $aImmunology 606 $aBiophysics 606 $aCancer Biology 606 $aPharmacology 615 0$aImmunology. 615 0$aBiophysics. 615 0$aCancer. 615 0$aPharmacology. 615 14$aImmunology. 615 24$aBiophysics. 615 24$aCancer Biology. 615 24$aPharmacology. 676 $a616.079 700 $aZeng$b Zhu$4aut$4http://id.loc.gov/vocabulary/relators/aut$01060286 702 $aXu$b Xiaofeng$4aut$4http://id.loc.gov/vocabulary/relators/aut 702 $aChen$b Dan$4aut$4http://id.loc.gov/vocabulary/relators/aut 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298443603321 996 $aDendritic Cells: Biophysics, Tumor Microenvironment and Chinese Traditional Medicine$92512271 997 $aUNINA