LEADER 04280nam  22005895  450 
001 9910298437103321
005 20220705163019.0
010   $a981-13-1286-9
024 7 $a10.1007/978-981-13-1286-1
035   $a(PPN)232474893
035   $a(CKB)4100000007110897
035   $a(MiAaPQ)EBC5598689
035   $a(DE-He213)978-981-13-1286-1
035   $a(EXLCZ)994100000007110897
100   $a20181102d2018      u|             0
101 0 $aeng
135   $aurcnu||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aNeural Regulation of Metabolism$b[electronic resource] /$fedited by Qi Wu, Ruimao Zheng
205   $a1st ed. 2018.
210  1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2018.
215   $a1 online resource (239 pages)
225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1090
311   $a981-13-1285-0 
327   $aFunctional interrogation of the AgRP neural circuits in control of appetite, body weight, and behaviors -- The Leptin Signalings -- The Leptin Resistance -- Neuronal cAMP/PKA Signaling and Energy Homeostasis -- POMC neurons feeding and reward -- Synaptic Regulation of Metabolism -- Glial Regulation of Energy Metabolism -- Regulation of Lipolysis in Adipose Tissue and Clinical Significance -- Electrophysiological mechanism of peripheral hormones and nutrients regulating energy homeostasis -- Central Circadian Clock Regulates Energy Metabolism -- Ghrelin signaling in immunometabolism and inflamm-aging -- Current genetic techniques in neural circuit control of feeding and energy metabolism.
330   $aThis book systemically describes the mechanisms underlying the neural regulation of metabolism. Metabolic diseases, including obesity and its associated conditions, currently affect more than 500 million people worldwide. Recent research has shown that the neural regulation of metabolism is a central mechanism that controls metabolic status physiologically and pathophysiologically. The book first introduces the latest studies on the neural and cellular mechanisms of hypothalamic neurons, hypothalamic glial cells, neural circuitries, cellular signaling pathways, and synaptic plasticity in the control of appetite, body weight, feeding-related behaviors and metabolic disorders. It then summarizes the humoral mechanisms by which critical adipocyte-derived hormones and lipoprotein lipase regulate lipid and glucose metabolism, and examines the role of the hypothalamus-sympathetic nerve, a critical nerve pathway from CNS to peripheral nervous system (PNS), in the regulation of metabolism in multiple tissues/organs. Furthermore, the book discusses the functions of adipose tissue in energy metabolism. Lastly, it explores dietary interventions to treat neural diseases and some of the emerging technologies used to study the neural regulation of metabolism. Presenting cutting-edge developments in the neural regulation of metabolism, the book is a valuable reference resource for graduate students and researchers in the field of neuroscience and metabolism.
410  0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1090
606   $aNeurosciences
606   $aHuman physiology
606   $aCytology
606   $aBiochemistry
606   $aNeurosciences$3http://scigraph.springernature.com/things/product-market-codes/B18006
606   $aHuman Physiology$3http://scigraph.springernature.com/things/product-market-codes/B13004
606   $aCell Biology$3http://scigraph.springernature.com/things/product-market-codes/L16008
606   $aBiochemistry, general$3http://scigraph.springernature.com/things/product-market-codes/L14005
615  0$aNeurosciences.
615  0$aHuman physiology.
615  0$aCytology.
615  0$aBiochemistry.
615 14$aNeurosciences.
615 24$aHuman Physiology.
615 24$aCell Biology.
615 24$aBiochemistry, general.
676   $a572.4
702   $aWu$b Qi$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aZheng$b Ruimao$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910298437103321
996   $aNeural Regulation of Metabolism$92544112
997   $aUNINA