LEADER 04949nam 22005295 450 001 9910298434903321 005 20200705084118.0 010 $a3-319-74080-6 024 7 $a10.1007/978-3-319-74080-5 035 $a(CKB)4100000004243583 035 $a(MiAaPQ)EBC5400864 035 $a(DE-He213)978-3-319-74080-5 035 $a(PPN)227400267 035 $a(EXLCZ)994100000004243583 100 $a20180522d2018 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aClinical Investigation /$fedited by Mieczyslaw Pokorski 205 $a1st ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (106 pages) 225 1 $aNeuroscience and Respiration ;$v1047 311 $a3-319-74079-2 327 $aPrognostic Value of Osteoprotegerin and sRANKL in Bronchoalveolar Lavage Fluid of Patients with Advanced Non-Small Cell Lung Cancer, W. Naumnik, I. P?o?ska, M. Ossoli?ska, J. Nikli?ski, and B. Naumnik -- Melatonin and Metformin Diminish Oxidative Stress in Heart Tissue in a Rat Model of High Fat Diet and Mammary Carcinogenesis, N. Kurhaluk, B. Bojkova, M. Radkowski, O.V. Zaitseva, S. Kyriienko, U. Demkow, and P.J. Winklewski -- Evaluation of the Implementation of Hospital Antibiotic Policy in Oncosurgery Ward: a Six-Year Experience, A. Nitsch-Osuch, D. Okrucinski, M. Dawgial?o, I. Go??biak, and E. Kuchar -- Surgical Correction of Pectus Excavatum by the Nuss Procedure: a 15-Year Experience Study, P. Cierpikowski, A. Rzechonek, P. B?asiak, H. Lisowska, G. Pniewski, and P. Le Pivertl -- Influence of Inhaled Corticosteroids on Bronchial Inflammation and Pulmonary Function in Chronic Obstructive Pulmonary Disease with Moderate Obstruction, I. Toczyska, E. Zwoli?ska, and A. Chcialowski -- Association between Vitamin D and Carboxy-terminal Cross-Linked Telopeptide of Type I Collagen in Children during Growth Hormone Replacement Therapy, E. Witkowska-S?dek, A. Stelmaszczyk-Emmel, A. Kucharska, U. Demkow, and B. Pyr?ak -- Weight Disorders in Short Children, P. Tomaszewski, A. Majcher, K. Milde, and R. Stupnicki -- Neutrophil Gelatinase-Associated Lipocalin: a Biomarker for Early Diagnosis of Urinary Tract Infections in Infants, G. Krzemie?, M. Pa?czyk-Tomaszewska, D. Adamczuk, I. Kotu?a, U. Demkow, and A. Szmigielska -- A Two-Week Fecal Microbiota Transplantation Course in Pediatric Patients with Inflammatory Bowel Disease, K. Karolewska-Bochenek, P. Grzesiowski, A. Banaszkiewicz, A. Gawronska, M. Kotowska, M. Dziekiewicz, P. Albrecht, A. Radzikowski, and I. Lazowska-Przeorek -- Specialized Pain Clinics in Primary Care: Common Diagnoses, Referral Patterns and Clinical Outcomes ? Novel Pain Management Model, Y. Fogelman, E. Carmeli, A. Minerbi, H. Baruch, and S. Vulfsons. . 330 $aClinical investigation plays an essential role in the differential diagnosis, biomarker development, and therapy and cure of diseases. The book presents a bench-to-bed approach, with broad empirical coverage by experienced practitioners. The articles include topics like cytokine receptors in lung cancer, conduciveness of oxidative stress to carcinogenesis, safety and effectiveness of surgical correction of deformed chest, diagnostic and treatment regimens in inflammation-ridden obstructive lung conditions, alterations in growth hormone secretion leading to disorders of growth and metabolism, microbiota transplantation in pediatric patients, and the promising markers of renal epithelial injury. Yet another issue concerns the restructuring of chronic pain management by establishing the community-based specialized pain clinics. The book aims to disseminate and deliberate on the latest interdisciplinary medical knowledge to enhance clinical outcomes. 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