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010   $a3-319-74932-3
024 7 $a10.1007/978-3-319-74932-7
035   $a(CKB)4100000003359361
035   $a(MiAaPQ)EBC5342044
035   $a(DE-He213)978-3-319-74932-7
035   $a(PPN)226696952
035   $a(EXLCZ)994100000003359361
100   $a20180406d2018      u|         0
101 0 $aeng
135   $aurcnu||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aMetabolic Interaction in Infection /$fedited by Ricardo Silvestre, Egídio Torrado
205   $a1st ed. 2018.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018.
215   $a1 online resource (478 pages)
225 1 $aExperientia Supplementum,$x2504-3692 ;$v109
311   $a3-319-74931-5 
327   $aPart I: A guide of metabolism during host-pathogen interactions -- 1. Cellular metabolism at a glance -- 2. Interaction between nutrition and metabolism -- 3. Interplay between metabolic sensors and cell signaling -- 4. Alterations on cellular redox states upon infection and implications for host cell homeostasis -- 5. Mitochondrial bioenergetics and dynamics during infection -- 6. Computational systems biology of metabolism in infection -- 7. Metabolomic-based methods in diagnosis and monitoring infection progression -- Part II: Microbial metabolic adaptation and pathogen rewiring of host cell metabolism during infection -- 8. Metabolic host response to intracellular infections -- 9. Protozoan parasites auxotrophies and metabolic dependencies -- 10. Viral manipulation of the host metabolic network -- 11. Metabolic regulation of innate immunity to fungal infection -- 12. Metabolic crosstalk between host and parasitic pathogens -- 13. Microbiome and gut dysbiosis.
330   $aThis book focuses on host?pathogen interactions at the metabolic level. It explores the metabolic requirements of the infectious agents, the microbial metabolic pathways that are dedicated to circumvent host immune mechanisms as well as the molecular mechanisms by which pathogens hijack host cell metabolism for their own benefit. Finally, it provides insights on the possible clinical and immunotherapeutic applications, as well as on the available experimental and analytical methods. The contributions break new ground in understanding the metabolic crosstalk between host and pathogen.
410  0$aExperientia Supplementum,$x2504-3692 ;$v109
606   $aMedicine$xResearch
606   $aBiology$xResearch
606   $aBiochemistry
606   $aMedical microbiology
606   $aBiomedical Research
606   $aBiochemistry
606   $aMedical Microbiology
615  0$aMedicine$xResearch.
615  0$aBiology$xResearch.
615  0$aBiochemistry.
615  0$aMedical microbiology.
615 14$aBiomedical Research.
615 24$aBiochemistry.
615 24$aMedical Microbiology.
676   $a574.8761
702   $aSilvestre$b Ricardo$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aTorrado$b Egídio$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910298433403321
996   $aMetabolic Interaction in Infection$92537521
997   $aUNINA