LEADER 03938nam  22006255  450 
001 9910298430303321
005 20200702214435.0
010   $a981-13-0481-5
024 7 $a10.1007/978-981-13-0481-1
035   $a(CKB)4100000006519868
035   $a(MiAaPQ)EBC5515254
035   $a(DE-He213)978-981-13-0481-1
035   $a(PPN)230536506
035   $a(EXLCZ)994100000006519868
100   $a20180912d2018      u|         0
101 0 $aeng
135   $aurcnu||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aGene and Cell Therapy: Biology and Applications /$fedited by Giridhara R. Jayandharan
205   $a1st ed. 2018.
210  1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2018.
215   $a1 online resource (316 pages)
311   $a981-13-0480-7 
327   $aChapter 1. Retroviral vectors in gene therapy -- Chapter 2. Adeno-associated virus vectors in gene therapy -- Chapter 3. Nanoparticle-mediated gene delivery -- Chapter 4. Viral/non-viral based hybrid vectors for gene therapy -- Chapter 5. Pharmaco-gene therapy: an alternate perspective -- Chapter 6. Aptamers - Novel molecules in therapeutics -- Chapter 7. Induced pluripotent stem cells -- Chapter 8. Hope or Hype: Stem cells as therapeutics in retinal degenerative diseases -- Chapter 9. Hematopoeitic stem cells: past, present and future.
330   $aRecent advances in stem cell biology, nanotechnology and gene therapy have opened new avenues for therapeutics. The availability of molecular therapeutics that rely on the delivery of DNA, RNA or proteins, harnessing enhanced delivery with nanoparticles, and the regenerative potential of stem cells (adult, embryonic or induced pluripotent stem cells) has had a tremendous impact on translational medicine. The chapters in this book cover a range of strategies for molecular and cellular therapies for human disease, their advantages, and central challenges to their widespread application. Potential solutions to these issues are also discussed in detail. Further, the book addresses numerous advances in the field of molecular therapeutics that will be of interest to the general scientific community. Lastly, the book provides specific examples of disease conditions for which these strategies have been transferred to the clinic. As such, it will be extremely useful for all students, researchers and clinicians working in the field of translational medicine and molecular therapeutics. .
606   $aGene therapy
606   $aStem cells
606   $aRegenerative medicine
606   $aTissue engineering
606   $aBiomedical engineering
606   $aMedical genetics
606   $aGene Therapy$3https://scigraph.springernature.com/ontologies/product-market-codes/B12020
606   $aStem Cells$3https://scigraph.springernature.com/ontologies/product-market-codes/L16010
606   $aRegenerative Medicine/Tissue Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/L16080
606   $aBiomedical Engineering/Biotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/B24000
606   $aGene Function$3https://scigraph.springernature.com/ontologies/product-market-codes/B12030
615  0$aGene therapy.
615  0$aStem cells.
615  0$aRegenerative medicine.
615  0$aTissue engineering.
615  0$aBiomedical engineering.
615  0$aMedical genetics.
615 14$aGene Therapy.
615 24$aStem Cells.
615 24$aRegenerative Medicine/Tissue Engineering.
615 24$aBiomedical Engineering/Biotechnology.
615 24$aGene Function.
676   $a616.042
702   $aJayandharan$b Giridhara R$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910298430303321
996   $aGene and Cell Therapy: Biology and Applications$92505682
997   $aUNINA