LEADER 03406nam  22005415  450 
001 9910298428403321
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010   $a981-13-1429-2
024 7 $a10.1007/978-981-13-1429-2
035   $a(CKB)4100000007003170
035   $a(MiAaPQ)EBC5553258
035   $a(DE-He213)978-981-13-1429-2
035   $a(PPN)231458576
035   $a(EXLCZ)994100000007003170
100   $a20181011d2018      u|         0
101 0 $aeng
135   $aurcnu||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aHeart Genomics /$fedited by Hong Jiang, Ming Liu
205   $a1st ed. 2018.
210  1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2018.
215   $a1 online resource (375 pages)
225 1 $aTranslational Bioinformatics,$x2213-2775 ;$v16
311   $a981-13-1428-4 
327   $aGenome-wide association studies of hypertension and several other cardiovascular diseases -- Cardiac transcriptome profile in heart diseases -- The Emerging Role of Epigenetics -- Mitochondria Genome Mutations and Cardiovascular Diseases -- GATA Transcription Factors and Cardiovascular Disease -- The Genetic Paradigm of WT1 Gene in Heart Development and Cardiac Repair -- Progress of genomics in hypertension-cardiac hypertrophy -- Progress of genomics in atherosclerosis-coronary heart disease and myocardial infarction -- Progress of genomics in cardiac conduction and rhythm disorders -- Progress of epigenetic changes in heart failure -- Progress of genetics in inherited cardiomyopathies-induced heart failure -- Warfarin and its pharmacogenomic study -- Gene therapy and genomic application in heart disease.
330   $aThis book elucidates how advances in genomics research are being applied in connection with heart diseases. It describes the development of genome-scale technologies and their applications to all areas of cardiac investigations, such as genomics, functional genomics, epigenomics, etc., and how they relate to a series of important breakthroughs in various heart diseases. Applying unbiased genomics, combined with a disease-focused and hypothesis-driven approach, represents a promising way to advance our understanding of cardiac diseases. The book offers an important reference work on introducing genomics in heart disease for all scientists and graduate students whose work involves genomics and cardiology, as well as for clinical physicians.
410  0$aTranslational Bioinformatics,$x2213-2775 ;$v16
606   $aHuman genetics
606   $aMolecular biology
606   $aCardiology
606   $aHuman Genetics$3https://scigraph.springernature.com/ontologies/product-market-codes/B12008
606   $aMolecular Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B1700X
606   $aCardiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33037
615  0$aHuman genetics.
615  0$aMolecular biology.
615  0$aCardiology.
615 14$aHuman Genetics.
615 24$aMolecular Medicine.
615 24$aCardiology.
676   $a616.12042
702   $aJiang$b Hong$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aLiu$b Ming$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910298428403321
996   $aHeart Genomics$92503185
997   $aUNINA