LEADER 04861nam  22006255  450 
001 9910298426703321
005 20251116195830.0
010   $a3-319-76735-6
024 7 $a10.1007/978-3-319-76735-2
035   $a(CKB)4100000004243736
035   $a(DE-He213)978-3-319-76735-2
035   $a(MiAaPQ)EBC5387334
035   $a(PPN)227400305
035   $a(EXLCZ)994100000004243736
100   $a20180507d2018      u|         0
101 0 $aeng
135   $aurnn#008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aOsteochondral Tissue Engineering $eChallenges, Current Strategies, and Technological Advances /$fedited by J. Miguel Oliveira, Sandra Pina, Rui L. Reis, Julio San Roman
205   $a1st ed. 2018.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018.
215   $a1 online resource (IX, 511 p. 86 illus., 79 illus. in color.)
225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1059
311 08$a3-319-76734-8 
327   $aPart I: Current Challenges in Osteochondral Repair and Regeneration: Trauma vs Disease -- Advances for treatment of knee OC defects -- Emerging Concepts in Treating Cartilage, Osteochondral Defects and Osteoarthritis of the Knee and Ankle -- Osteoarthritis: Trauma Vs Disease -- Surgical Treatment Paradigms of Ankle Lateral Instability, Osteochondral Defects and Impingement -- Part II: Viscosupplementation -- Clinical management in early OA -- Hyaluronic Acid -- Semi-IPNs and IPNs Based Hydrogels -- Promising biomolecules -- Part III: Technological Advances in Osteochondral Tissue Engineering -- Nanoparticles-based systems for Osteochondral Tissue Engineering -- Stem cells for osteochondral regeneration -- PRP Therapy -- Enhancing biological and biomechanical fixation of osteochondral scaffold: a grand challenge -- Part IV: Osteochondral Tissue Engineering approaches -- Combination of polymeric supports and drug delivery systems for ostechondral regeneration -- Osteochondral Angiogenesis and Promoted Vascularization: New Therapeutic Target -- Models Of Disease -- Part V: In vitro models for Osteochondral Regeneration -- Tissue Engineering Strategies for Osteochondral Repair -- In vitro mimetic models for the bone-cartilage interface regeneration -- Bioreactors and microfluidics for osteochondral interface maturation -- Part VI: In vivo models for Osteochondral Regeneratio -- nSmall Animal Models -- Large animal models for Osteochondral Regeneration -- Index.
330   $aThis book covers the most recent developments in the field of osteochondral tissue engineering (OCTE) and covers in detail the concepts and current challenges for bone and cartilage repair and regeneration. Specific topics include viscosupplementation, biologicals, tissue engineering approaches, in vitro and in vivo models, and technological advances with stem cells, bioreactors, and microfluidics. Osteochondral Tissue Engineering: Challenges, Current Strategies, and Technological Advances presents challenges and strategies in the field of osteochondral regeneration and serves as a core reference for biomedical engineering students and a wide range of established researchers and professionals working in orthopedics.
410  0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1059
606   $aRegenerative medicine
606   $aTissue engineering
606   $aBiomedical engineering
606   $aBiomedical materials
606   $aRegenerative Medicine/Tissue Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/L16080
606   $aBiomedical Engineering/Biotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/B24000
606   $aBiomaterials$3https://scigraph.springernature.com/ontologies/product-market-codes/Z13000
606   $aBiomedical Engineering and Bioengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/T2700X
615  0$aRegenerative medicine.
615  0$aTissue engineering.
615  0$aBiomedical engineering.
615  0$aBiomedical materials.
615 14$aRegenerative Medicine/Tissue Engineering.
615 24$aBiomedical Engineering/Biotechnology.
615 24$aBiomaterials.
615 24$aBiomedical Engineering and Bioengineering.
676   $a612.028
676   $a571.538
702   $aOliveira$b J. Miguel$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aPina$b Sandra$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aReis$b Rui L.$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aSan Roma?n$b Julio$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910298426703321
996   $aOsteochondral Tissue Engineering$92537513
997   $aUNINA