LEADER 04491nam 22005415 450 001 9910298424703321 005 20200703054419.0 010 $a981-13-1756-9 024 7 $a10.1007/978-981-13-1756-9 035 $a(CKB)4100000007003097 035 $a(MiAaPQ)EBC5553254 035 $a(DE-He213)978-981-13-1756-9 035 $a(PPN)231461410 035 $a(EXLCZ)994100000007003097 100 $a20181010d2018 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAdvances in Pain Research: Mechanisms and Modulation of Chronic Pain /$fedited by Bai-Chuang Shyu, Makoto Tominaga 205 $a1st ed. 2018. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2018. 215 $a1 online resource (x, 265 pages) $cillustrations 225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1099 311 $a981-13-1755-0 327 $aMolecular Mechanisms of the sense of touch: an overview of mechanical transduction and transmission in Merkel discs of whisker hair follicles and some clinical perspectives -- TRP Channels in Nociception and Pathological Pain -- Involvement of TRPV1-ANO1 interactions in pain enhancing mechanisms -- Roles of ASICs in Nociception and Proprioception -- Tackling pain associated with rheumatoid arthritis: Proton-sensing receptors -- Intra-Fascicular Local Anesthetic Injection damages Peripheral Nerve Induced Neuropathic Pain -- Microglia in the CNS and neuropathic pain -- Descending noradrenergic inhibition ?an important mechanism of gabapentin analgesia in neuropathic pain -- Chronic neuropathic pain protects heart from ischemia reperfusion injury -- Knowing the neuronal mechanism of spontaneous pain to treat chronic pain in future -- Role of Neuroinflammation in Opioid Tolerance: Translational Evidence from Human-to-Rodent Studies -- Neural mechanisms of offset analgesia -- Cortical LTP: A synaptic model for chronic pain -- Pain-associated neural plasticity in the parabrachial to central amygdala circuit -- Electrophysiological signature of pain -- Neuroimaging Studies of Primary Dysmenorrhea -- Brain reward circuit and pain -- The Involvement of P2X7 Receptors and BDNF in the Pathogenesis of Central Post Stroke Pain -- Melatonin: A new-generation therapy for reducing chronic pain and improving sleep disorder-related pain -- Central poststroke pain, comorbidity, and associated symptoms in animal and human models . 330 $aThis book summarizes the latest advances in pain research. All the chapters were contributed by speakers from Asian Pain Symposium (APS) on Acute and Chronic Pain, which was held in Taipei in 2017. Founded in Kyoto, Japan in 2000, the APS serves as a platform for scientists to present recent findings in pain research and discuss research orientation in this field. APS 2017 focused on novel strategies for pain treatment. Written by experts from various disciplines, from molecular to functional, and from basic to clinic studies, this book is composed of 19 review articles on the physiology and pathology of pain in these research fields. Specific topics include circuitry, neurotransmitter, physiology, behavior, neuropathology, pharmacology, and the treatments for neuropathic pain disorders. The book is a valuable resource for researchers and graduate students in pain medicine and neuroscience. 410 0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1099 606 $aNeurosciences 606 $aHuman physiology 606 $aMolecular biology 606 $aNeurosciences$3https://scigraph.springernature.com/ontologies/product-market-codes/B18006 606 $aHuman Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B13004 606 $aMolecular Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B1700X 615 0$aNeurosciences. 615 0$aHuman physiology. 615 0$aMolecular biology. 615 14$aNeurosciences. 615 24$aHuman Physiology. 615 24$aMolecular Medicine. 676 $a616.0472 702 $aShyu$b Bai-Chuang$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aTominaga$b Makoto$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298424703321 996 $aAdvances in Pain Research: Mechanisms and Modulation of Chronic Pain$92500534 997 $aUNINA