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024 7 $a10.1007/978-3-319-71232-1
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035   $a(DE-He213)978-3-319-71232-1
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100   $a20180625d2018      u|             0
101 0 $aeng
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181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aBiology of Chlamydia$b[electronic resource] /$fedited by Georg Häcker
205   $a1st ed. 2018.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018.
215   $a1 online resource (243 pages)
225 1 $aCurrent Topics in Microbiology and Immunology,$x0070-217X ;$v412
311   $a3-319-71230-6 
327   $aCell wall biosynthesis in Chlamydia -- Genetic manipulation in Chlamydia --  Early events in the Chlamydia developmental cycle --  Subversion of the host cell cytoskeleton by Chlamydia -- Cell-autonomous host defence against Chlamydia infection -- The enigma of long-term infection: are there quiescent or 'persistent' Chlamydia?- Mechanisms of immunopathogenesis during chlamydial infections -- Protective adaptive immune response and prospects for a vaccine -- The hidden genomics of Chlamydia trachomatis.
330   $aThe genus Chlamydia encompasses a number of species of obligate intracellular bacteria, including important human pathogens like the most common bacterial agent of sexually transmitted disease. This volume reviews current knowledge of chlamydial biology, covering the unusual structure of the bacteria ? which alternate between metabolically almost inactive and fast-dividing forms. It also discusses the ways in which Chlamydia manipulates the host cytoskeleton and subverts the host cell?s defence, and illustrates how genomics have begun to uncover the diversity and complexity of chlamydial strains that look very similar but may cause distinct forms of disease. Further, it describes how techniques are now finally being established that can genetically modify Chlamydia, and discusses why such modification is still very difficult and what progress we can expect. Lastly, it presents our current understanding of chlamydial disease: what do we know about chronic infections, what are the mechanisms of inflammatory damage, and what are the prospects of a vaccine? Written be specialists in these various areas, the book is a valuable work of reference for students and scientists with an interest in the molecular, cellular and immunobiology of these fascinating bacteria.
410  0$aCurrent Topics in Microbiology and Immunology,$x0070-217X ;$v412
606   $aMedical microbiology
606   $aImmunology
606   $aInfectious diseases
606   $aMedical Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B16003
606   $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000
606   $aInfectious Diseases$3https://scigraph.springernature.com/ontologies/product-market-codes/H33096
615  0$aMedical microbiology.
615  0$aImmunology.
615  0$aInfectious diseases.
615 14$aMedical Microbiology.
615 24$aImmunology.
615 24$aInfectious Diseases.
676   $a614.5735
702   $aHäcker$b Georg$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910298421503321
996   $aBiology of Chlamydia$92536232
997   $aUNINA