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010   $a3-319-98785-2
024 7 $a10.1007/978-3-319-98785-9
035   $a(CKB)4100000005958135
035   $a(MiAaPQ)EBC5500274
035   $a(DE-He213)978-3-319-98785-9
035   $a(PPN)22991960X
035   $a(EXLCZ)994100000005958135
100   $a20180825d2018      u|             0
101 0 $aeng
135   $aurcnu||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aAntiseptic Stewardship$b[electronic resource] $eBiocide Resistance and Clinical Implications /$fby Günter Kampf
205   $a1st ed. 2018.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018.
215   $a1 online resource (722 pages)
311   $a3-319-98784-4 
327   $a1. Chemical characterization -- 2. Types of application -- 2a. Approval by ECHA -- 2b. Approval by EPA -- 2c. Amounts per type of application (overall environmental impact) -- 3. Spectrum of antimicrobial activity -- 3a. Bactericidal activity -- 3b. Fungicidal activity -- 3c. Mycobactericidal activity -- 3d. Virucidal activity -- 3e. Sporicidal activity -- 4. Natural resistances -- 5. Adaptation after exposure -- 5a. Per type of typical application -- 6. 7. Cross-resistance to other biocidal agents -- 8. Cross-resistances to antibiotics -- 9. Proposal for responsible use (antiseptic stewardship).
330   $aVVarious antiseptic agents, such as chlorhexidine, are used for different applications, e.g. in healthcare, veterinary medicine, animal production and household products, including cosmetics. However, not all antiseptic agents provide significant health benefits, especially in some products used in human medicine (alcohol-based hand rubs, antimicrobial soaps). While some products (antimicrobial soaps, surface disinfectants, instrument disinfectants, wound antiseptics) may contain one or more biocidal agents with a comparable antimicrobial efficacy but large differences in their potential for microbial adaptation and tolerance. An increased bacterial resistance has been described for various antimicrobial agents, sometimes including a cross-resistance to antibiotics. The book is the first comprehensive reference resource on antiseptic agents, including their efficacy, natural and acquired resistance, adaptation, and cross-resistance. It also discusses their and appropriate use in terms of a balance between their efficacy and the risk of acquired bacterial resistance / tolerance. Focusing on human and veterinary medicine and household products, it helps readers make informed decisions concerning against antiseptic products based on their composition. The book contributes to reduce any unnecessary selection pressure towards emerging pathogens and to keep the powerful antiseptic agents for all those applications that have a clear benefit (e.g. reduction of healthcare-associated infection).
606   $aMedical microbiology
606   $aInfectious diseases
606   $aEnvironmental health
606   $aMedical Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B16003
606   $aInfectious Diseases$3https://scigraph.springernature.com/ontologies/product-market-codes/H33096
606   $aEnvironmental Health$3https://scigraph.springernature.com/ontologies/product-market-codes/U18005
615  0$aMedical microbiology.
615  0$aInfectious diseases.
615  0$aEnvironmental health.
615 14$aMedical Microbiology.
615 24$aInfectious Diseases.
615 24$aEnvironmental Health.
676   $a614.48
700   $aKampf$b Günter$4aut$4http://id.loc.gov/vocabulary/relators/aut$01062572
906   $aBOOK
912   $a9910298412003321
996   $aAntiseptic Stewardship$92526732
997   $aUNINA