LEADER 04405nam  22005775  450 
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010   $a3-319-16769-3
024 7 $a10.1007/978-3-319-16769-5
035   $a(CKB)4100000006374594
035   $a(MiAaPQ)EBC5509278
035   $a(DE-He213)978-3-319-16769-5
035   $a(PPN)230540139
035   $a(EXLCZ)994100000006374594
100   $a20180903d2018      u|         0
101 0 $aeng
135   $aurcnu||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aEpigenetic Regulation of Skin Development and Regeneration /$fedited by Vladimir A. Botchkarev, Sarah E. Millar
205   $a1st ed. 2018.
210  1$aCham :$cSpringer International Publishing :$cImprint: Humana,$d2018.
215   $a1 online resource (330 pages)
225 1 $aStem Cell Biology and Regenerative Medicine,$x2196-8985
311   $a3-319-16768-5 
320   $aIncludes bibliographical references and index.
327   $aPreface -- Chapter 1 All Roads Go to the Nucleus -- Chapter 2 DNA methylation as an epigenetic memory keeper during skin development and regeneration -- Chapter 3 Polycomb genes and their roles in skin development and regeneration -- Chapter 4 Trithorax genes in the control of keratinocyte differentiation -- Chapter 5 Histone deacetylase functions in epidermal development, homeostasis and cancer -- Chapter 6 The role of ATP-dependent chromatin remodeling in the control of epidermal differentiation and skin stem cell activity -- Chapter 7 Orchestrated Role of microRNAs in Skin Development and Regeneration -- Chapter 8 Non-coding genome and its role in the control of gene expression -- Chapter 9 RNA modifications in the control of epidermal differentiation and stem cell activity -- Chapter 10 Enhancer-Promoter Interactions and Their Role in the Control of Epidermal Differentiation -- Chapter 11 Nuclear lamina as an interface between cytoskeleton and chromatin -- Chapter 12 Epigenetic mechanisms in the control of skin wound healing.
330   $aThis indispensable volume highlights recent studies identifying epigenetic mechanisms as essential regulators of skin development, stem cell activity and regeneration. Chapters are contributed by leading experts and promote the skin as an accessible model system for studying mechanisms that control organ development and regeneration. The timely discussions contained throughout are of broad relevance to other areas of biology and medicine and can help inform the development of novel therapeutics for skin disorders as well as new approaches to skin regeneration that target the epigenome. Part of the highly successful Stem Cells and Regenerative Medicine series, Epigenetic Regulation of Skin Development and Regeneration uncovers the fundamental significance of epigenetic mechanisms in skin development and regeneration, and emphasizes the development of new therapies for a number of skin disorders, such as pathological conditions of epidermal differentiation, pigmentation and carcinogenesis. At least six categories of researchers will find this book essential, including stem cell, developmental, hair follicle or molecular biologists, and gerontologists or clinical dermatologists. .
410  0$aStem Cell Biology and Regenerative Medicine,$x2196-8985
606   $aStem cells
606   $aRegenerative medicine
606   $aTissue engineering
606   $aDermatology
606   $aStem Cells$3https://scigraph.springernature.com/ontologies/product-market-codes/L16010
606   $aRegenerative Medicine/Tissue Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/L16080
606   $aDermatology$3https://scigraph.springernature.com/ontologies/product-market-codes/H1900X
615  0$aStem cells.
615  0$aRegenerative medicine.
615  0$aTissue engineering.
615  0$aDermatology.
615 14$aStem Cells.
615 24$aRegenerative Medicine/Tissue Engineering.
615 24$aDermatology.
676   $a572.645
702   $aBotchkarev$b Vladimir A$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aMillar$b Sarah E$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910298406503321
996   $aEpigenetic Regulation of Skin Development and Regeneration$92533184
997   $aUNINA