LEADER 03587nam 22006495 450 001 9910298405003321 005 20200702092818.0 010 $a3-319-77495-6 024 7 $a10.1007/978-3-319-77495-4 035 $a(CKB)3850000000032741 035 $a(MiAaPQ)EBC5448095 035 $a(DE-He213)978-3-319-77495-4 035 $a(PPN)229505236 035 $a(EXLCZ)993850000000032741 100 $a20180705d2018 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAcute Neuronal Injury $eThe Role of Excitotoxic Programmed Cell Death Mechanisms /$fedited by Denson G. Fujikawa 205 $a2nd ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (212 pages) 311 $a3-319-77494-8 327 $aIntroduction -- Excitotoxic programmed cell death involves caspase-independent mechanisms -- To survive or to die: how neurons deal with it -- Oxidative damage mechanisms in traumatic brain injury and antioxidant neuroprotective approaches -- Mitochondrial damage in traumatic CNS injury -- Neuroprotective agents target molecular mechanisms of programmed cell death after traumatic brain injury -- Involvement of apoptosis-inducing factor (AIF) in neuronal death following cerebral ischemia -- Apoptosis-inducing factor translocation to nuclei after transient global ischemia -- Necroptosis in cerebral ischemia -- Histological and elemental changes in ischemic stroke -- Hypoglycemic brain damage -- Activation of caspase-independent programmed pathways in seizure-induced neuronal necrosis -- Conclusion. 330 $aAn overview of the biochemical mechanisms that produce acute nerve cell death in the brain. Covers injuries and disorders including stroke, brain and spinal cord trauma, hypoglycemic coma, and prolonged epileptic seizures. All of these lead to high concentrations of calcium in nerve cells which, in turn, causes degradation of cytoplasmic proteins, cleavage of nuclear DNA, and eventually cell death. The Second Edition contains 11 thoroughly updated chapters and 3 additional chapters that did not appear in the previous edition. 606 $aNeurosciences 606 $aNeurology 606 $aPathology 606 $aCytology 606 $aNeurobiology 606 $aPsychiatry 606 $aNeurosciences$3https://scigraph.springernature.com/ontologies/product-market-codes/B18006 606 $aNeurology$3https://scigraph.springernature.com/ontologies/product-market-codes/H36001 606 $aPathology$3https://scigraph.springernature.com/ontologies/product-market-codes/H4800X 606 $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008 606 $aNeurobiology$3https://scigraph.springernature.com/ontologies/product-market-codes/L25066 606 $aPsychiatry$3https://scigraph.springernature.com/ontologies/product-market-codes/H53003 615 0$aNeurosciences. 615 0$aNeurology. 615 0$aPathology. 615 0$aCytology. 615 0$aNeurobiology. 615 0$aPsychiatry. 615 14$aNeurosciences. 615 24$aNeurology. 615 24$aPathology. 615 24$aCell Biology. 615 24$aNeurobiology. 615 24$aPsychiatry. 676 $a616.8 702 $aFujikawa$b Denson G$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298405003321 996 $aAcute Neuronal Injury$92522653 997 $aUNINA LEADER 06084nam 22008295 450 001 9910298298803321 005 20200630233854.0 010 $a81-322-2235-0 024 7 $a10.1007/978-81-322-2235-4 035 $a(CKB)3710000000356847 035 $a(EBL)1974138 035 $a(SSID)ssj0001451860 035 $a(PQKBManifestationID)11789696 035 $a(PQKBTitleCode)TC0001451860 035 $a(PQKBWorkID)11478271 035 $a(PQKB)10132281 035 $a(DE-He213)978-81-322-2235-4 035 $a(MiAaPQ)EBC1974138 035 $a(PPN)184494338 035 $a(EXLCZ)993710000000356847 100 $a20150209d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aRecent Advances in Lichenology$b[electronic resource] $eModern Methods and Approaches in Lichen Systematics and Culture Techniques, Volume 2 /$fedited by Dalip Kumar Upreti, Pradeep K. Divakar, Vertika Shukla, Rajesh Bajpai 205 $a1st ed. 2015. 210 1$aNew Delhi :$cSpringer India :$cImprint: Springer,$d2015. 215 $a1 online resource (240 p.) 300 $aDescription based upon print version of record. 311 $a81-322-2234-2 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $a1.  Lichenization: the origins of a fungal life-style -- 2. The dynamic discipline of species delimitation: Progress towards effectively recognizing species boundaries in natural populations -- 3. Molecular phylogenetic and phylogenomic approaches in studies of lichen systematics and evolution -- 4. High-throughput sequencing in studies of lichen population biology -- 5. Type-I NR-PKS gene characterization of the cultured lichen mycobiont Xanthoparmelia substrigosa (Ascomycota) -- 6. Endolichenic fungi in Kumaun Himalaya: a case study -- 7. The diversity of lichenised fungi: ecosystem functions and ecosystem services -- 8. In-Vitro Culture of Lichen Partners: Need and Implications -- 9. Biochemical Diversity and Ecology of Lichen-forming Fungi. Lichen Substances, chemosyndromic variation and origin of Polyketide-type metabolites (biosynthetic pathways) -- 10. Lichen substances and their biological activities -- 11. Anti-cancer activity of lichen metabolites and their mechanisms at the molecular level -- 12. Lichen dyes: Current scenario and future prospects. 330 $aThis book discusses in detail molecular, mycobiont culture, biomonitoring and bioprospection of lichens, providing insights into advances in different fields of lichenology by applying modern techniques and approaches and examining how their application has enhanced or changed classical approaches. It offers a valuable resource, especially for beginners, students and researchers from different academic backgrounds interested in the study of lichens. In recent years, the introduction of modern analytical techniques and approaches has significantly improved our understanding of the environment, including lichens. Lichens are unique organisms which possess untapped potential as effective and reliable bioindicators, sources of therapeutic phytochemicals, and as excellent extremophiles. The unique and peculiar characteristics of lichens underline the need for a multidimensional approach to explore their potential in various fields of environment science, botany and chemistry. Modern techniques, especially molecular techniques, have greatly enriched the field of lichen taxonomy and its position in the plant kingdom, revealing little-known species and exploring their evolutionary history, while multivariate analysis and GIS approaches have established lichens as an ideal and reliable tool for monitoring air pollution. Advanced culture techniques have expanded the pharmacological applications of lichens, which was formerly restricted due to their small biomass. The advent of sophisticated analytical instrumentation has now facilitated the isolation and characterization of lichens? bioactive constituents, even in lower concentrations, as well as the estimation of their stress responses at different levels of pollution. As lichen diversity is adversely affected by increasing air pollution, there is a pressing need to develop effective management practices to conserve, restore and document lichen diversity. 606 $aPlant genetics 606 $aMicrobiology 606 $aMetabolism 606 $aPlants$vClassification 606 $aPlants$vClassification 606 $aClimatic changes 606 $aPlant Genetics and Genomics$3https://scigraph.springernature.com/ontologies/product-market-codes/L32020 606 $aMicrobiology$3https://scigraph.springernature.com/ontologies/product-market-codes/L23004 606 $aMetabolomics$3https://scigraph.springernature.com/ontologies/product-market-codes/L15030 606 $aPlant Systematics/Taxonomy/Biogeography$3https://scigraph.springernature.com/ontologies/product-market-codes/L24051 606 $aClimate Change$3https://scigraph.springernature.com/ontologies/product-market-codes/U12007 615 0$aPlant genetics. 615 0$aMicrobiology. 615 0$aMetabolism. 615 0$aPlants 615 0$aPlants 615 0$aClimatic changes. 615 14$aPlant Genetics and Genomics. 615 24$aMicrobiology. 615 24$aMetabolomics. 615 24$aPlant Systematics/Taxonomy/Biogeography. 615 24$aClimate Change. 676 $a570 676 $a571.6 676 $a577.27 676 $a578.012 676 $a578.09 676 $a579 676 $a581.35 702 $aUpreti$b Dalip Kumar$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aDivakar$b Pradeep K$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aShukla$b Vertika$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aBajpai$b Rajesh$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298298803321 996 $aRecent Advances in Lichenology$92503010 997 $aUNINA