LEADER 04471nam 22005895 450 001 9910298397103321 005 20200703102531.0 010 $a3-319-95294-3 024 7 $a10.1007/978-3-319-95294-9 035 $a(CKB)4100000007103005 035 $a(MiAaPQ)EBC5596999 035 $a(DE-He213)978-3-319-95294-9 035 $a(PPN)231461380 035 $a(EXLCZ)994100000007103005 100 $a20181027d2018 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBiomechanics in Oncology$b[electronic resource] /$fedited by Cheng Dong, Nastaran Zahir, Konstantinos Konstantopoulos 205 $a1st ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (xii, 376 pages) $cillustrations 225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1092 311 $a3-319-95293-5 320 $aIncludes bibliographical references and index. 327 $aBiomaterials in Mechano-oncology: Means to Tune Materials to Study Cancer -- Traction Force Microscopy for Non-Invasive Imaging of Cell Forces -- Non-Invasive Imaging: Brillouin Confocal Microscopy -- Exposing Cell-itary Confinement: Understanding The Mechanisms Of Confined Single Cell Migration -- Modeling Cell Migration Mechanics -- Engineered models of metastasis with application to study cancer biomechanics -- Microenvironment influences cancer cell mechanics from tumor growth to metastasis -- From Cancer Immunoediting to New Strategies in Cancer Immunotherapy: The Roles of Immune Cells and Mechanics in Oncology -- Biomechanics of the circulating tumor cell microenvironment -- Mechanics of the cell nucleus -- Mechanical Forces in Tumor Angiogenesis -- DNA Mechanics and Topology -- Design of Fiber Networks for Studying Metastatic Invasion -- Extracellular matrix stiffness exists in a feedback loop that drives tumor progression -- Platelet-Based Drug Delivery for Cancer Applications -- The National Cancer Institute Investment in Biomechanics in Oncology Research. 330 $aThis book covers multi-scale biomechanics for oncology, ranging from cells and tissues to whole organ. Topics covered include, but not limited to, biomaterials in mechano-oncology, non-invasive imaging techniques, mechanical models of cell migration, cancer cell mechanics, and platelet-based drug delivery for cancer applications. This is an ideal book for graduate students, biomedical engineers, and researchers in the field of mechanobiology and oncology. This book also: Describes how mechanical properties of cancer cells, the extracellular matrix, tumor microenvironment and immuno-editing, and fluid flow dynamics contribute to tumor progression and the metastatic process Provides the latest research on non-invasive imaging, including traction force microscopy and brillouin confocal microscopy Includes insight into NCIs? role in supporting biomechanics in oncology research Details how biomaterials in mechano-oncology can be used as a means to tune materials to study cancer. 410 0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1092 606 $aBiomedical engineering 606 $aCancer research 606 $aOncology   606 $aBiomedical Engineering/Biotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/B24000 606 $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001 606 $aBiomedical Engineering and Bioengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/T2700X 606 $aOncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33160 615 0$aBiomedical engineering. 615 0$aCancer research. 615 0$aOncology  . 615 14$aBiomedical Engineering/Biotechnology. 615 24$aCancer Research. 615 24$aBiomedical Engineering and Bioengineering. 615 24$aOncology. 676 $a573.1536 702 $aDong$b Cheng$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aZahir$b Nastaran$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aKonstantopoulos$b Konstantinos$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298397103321 996 $aBiomechanics in Oncology$92496867 997 $aUNINA