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024 7 $a10.1007/978-1-4939-1112-7
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100   $a20140724d2014      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aCholesterol Transporters of the START Domain Protein Family in Health and Disease $eSTART Proteins - Structure and Function /$fedited by Barbara J. Clark, Douglas  M. Stocco
205   $a1st ed. 2014.
210  1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2014.
215   $a1 online resource (197 p.)
300   $aDescription based upon print version of record.
311   $a1-4939-1111-2 
320   $aIncludes bibliographical references and index at the end of each chapters.
327   $aAn Introduction to the Steroidogenic Acute Regulatory Protein (StAR)-related Lipid Transfer Domain Protein Family -- The Steroidogenic Acute Regulatory Protein (StAR) -- START domain protein structure and ligand specificity -- Congenital Lipoid Adrenal Hyperplasia -- Steroidogenic Acute Regulatory protein (StAR) and Atherogenesis -- STARD3: a lipid transfer protein in breast cancer and cholesterol trafficking -- The STARD4 subfamily: STARD4 and STARD5 in cholesterol metabolism -- START proteins in non-vesicular cholesterol transport -- Index.
330   $aNon-vesicular intracellular cholesterol transport is an important mechanism for maintaining membrane cholesterol homeostasis. Recent reports of studies directed at soluble cholesterol transport proteins indicate that aberrant expression of the START proteins may contribute to disease states associated with disorders in cholesterol homeostasis. This is an exciting new direction in the field and the purpose of this book will be to highlight the current research directed at potential roles for the START family in diabetes, cancer, and atherogenesis. This book also provides a personal and historical perspective of the discovery-to-publication journey that the authors had for their particular START domain family member. The goal will be to provide perspectives to graduate students, post-doctoral fellows, and endocrinology fellows on the research discovery process.
606   $aEndocrinology
606   $aProteins
606   $aMedicine
606   $aEndocrinology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33053
606   $aProtein Science$3https://scigraph.springernature.com/ontologies/product-market-codes/L14040
606   $aBiomedicine, general$3https://scigraph.springernature.com/ontologies/product-market-codes/B0000X
615  0$aEndocrinology.
615  0$aProteins.
615  0$aMedicine.
615 14$aEndocrinology.
615 24$aProtein Science.
615 24$aBiomedicine, general.
676   $a572.5795
676   $a572.6
676   $a610
676   $a616.4
702   $aClark$b Barbara J$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aStocco$b Douglas  M$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910298350803321
996   $aCholesterol Transporters of the START Domain Protein Family in Health and Disease$92537305
997   $aUNINA