LEADER 02646aam 2200529I 450 001 9910709596403321 005 20260430112032.0 024 8 $aGOVPUB-C13-1de4b420305cbab0c2e654b1cd03fc7f 035 $a(CKB)5470000002479032 035 $a(OCoLC)958885813 035 $a(DGPO)001073859 035 $a(EXLCZ)995470000002479032 100 $a20160921d2016 ua 0 101 0 $aeng 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aOAGi/NIST workshop on open cloud architecture for smart manufacturing /$fNenad Ivezic; Boonserm Kulvatunyou; Yan Lu; Yunsu Lee; Jaehun Lee; Albert Jones; Simon Frechette 210 1$aGaithersburg, MD :$cU.S. Dept. of Commerce, National Institute of Standards and Technology,$d2016. 215 $a1 online resource (71 pages) $cillustrations (color) 225 1 $aNISTIR ;$v8124 300 $aApril 2016. 300 $aContributed record: Metadata reviewed, not verified. Some fields updated by batch processes. 300 $aTitle from PDF title page (viewed April 30, 2016). 320 $aIncludes bibliographical references. 330 3 $aThis report summarizes the results from the OAGi/NIST Workshop on Open Cloud Architecture for Smart Manufacturing, which was held at the National Institute of Standards and Technology on May 5, 2015. The workshop was a forum for manufacturers and providers of IoT technologies, Cloud platforms, and manufacturing services to share their visions, and identify and prioritize barriers to adoption of Cloud-enabling capabilities and technologies, forming a basis for future follow-on events. The report (1) includes summaries as well as full presentations delivered at the workshop; (2) identifies and prioritizes technical issues; (3) summarizes the discussions that took place during the workshop; and (4) provides the conclusions that emerged from the presentations and discussions. 606 $aInternet of things 606 $aManufacturing processes 615 0$aInternet of things. 615 0$aManufacturing processes. 700 $aIvezic$b Nenad$01392969 701 $aFrechette$b Simon$01392970 701 $aIvezic$b Nenad$01392969 701 $aJones$b Albert$01391942 701 $aKulvatunyou$b Boonserm$01392971 701 $aLee$b Jaehun$01392972 701 $aLee$b Yunsu$01392973 701 $aLu$b Yan$0653112 712 02$aNational Institute of Standards and Technology (U.S.).$bEngineering Laboratory. 801 0$bNBS 801 1$bNBS 801 2$bGPO 801 2$bNBS 906 $aBOOK 912 $a9910709596403321 996 $aOAGi$93448516 997 $aUNINA LEADER 05373nam 22006615 450 001 9910298350603321 005 20260810150110.0 010 $a1-4939-1227-5 024 7 $a10.1007/978-1-4939-1227-8 035 $a(CKB)3710000000225189 035 $a(EBL)1802650 035 $a(SSID)ssj0001338286 035 $a(PQKBManifestationID)11898417 035 $a(PQKBTitleCode)TC0001338286 035 $a(PQKBWorkID)11337607 035 $a(PQKB)10540672 035 $a(MiAaPQ)EBC1802650 035 $a(DE-He213)978-1-4939-1227-8 035 $a(PPN)180627929 035 $a(EXLCZ)993710000000225189 100 $a20140822d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aCardiac Energy Metabolism in Health and Disease /$fedited by Gary D. Lopaschuk, Naranjan S. Dhalla 205 $a1st ed. 2014. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2014. 215 $a1 online resource (301 p.) 225 1 $aAdvances in Biochemistry in Health and Disease,$x2512-2150 ;$v11 300 $aDescription based upon print version of record. 311 08$a1-322-13333-6 311 08$a1-4939-1226-7 320 $aIncludes bibliographical references and index. 327 $aPart 1. Control of Energy Metabolism -- 1. A Primer on Carbohydrate Metabolism in the Heart -- 2. Lipoproteins: A Source of Cardiac Lipids -- 3. Role of Lipoprotein Lipase in Fatty Acid Delivery to the Heart -- 4. Control of Myocardial Fatty Acid Uptake -- 5. Cardiac Energy Metabolism in Heart Failure Associated with Obesity and Diabetes -- 6. Transcriptional Control of Mitochondrial Biogenesis and Maturation -- 7. Relationship between Substrate Metabolism and Cardiac Efficiency -- 8. Acetylation in the Control of Mitochondrial Metabolism and Integrity -- Part 2. Alteration in Energy Metabolism -- 9. Adrenergic Control of Cardiac Fatty Acid Oxidation in Diabetes -- 10. The Myocardial Creatine Kinase System in the Normal, Ischaemic and Failing Heart -- 11. Fuel Metabolism Plasticity in Pathological Cardiac Hypertrophy and Failure -- 12. Defects in Mitochondrial Oxidative Phosphorylation in Hearts Subjected to Ischemia-Reperfusion Injury -- 13. The Role of AMPK in the Control of Cardiac Hypertrophy -- 14. The Role of Incomplete Fatty Acid Oxidation in the Development of Cardiac Insulin Resistance -- Part 3. Optimization of Energy Metabolism -- 15. Metabolic Therapy for the Ischemic Heart -- 16. Inhibition of Fatty Acid Oxidation to Treat Heart Failure in Patients -- 17. Cardiac Metabolic Protection for the Newborn Heart -- 18. Targeting Transcriptional Control of Fatty Acid Oxidation to Treat Heart Disease. 330 $aThe heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP.  The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy, and any change in this energy supply can seriously compromise cardiac function.  It has emerged that alterations in cardiac energy metabolism are a major contributor to the development of a number of different forms of heart disease.  It is also now known that optimizing energy metabolism in the heart is a viable and important approach to treating various forms of heart disease. Cardiac Energy Metabolism in Health and Disease describes the research advances that have been made in understanding what controls cardiac energy metabolism at molecular, transcriptional, and physiological levels.  It also describes how alterations in energy metabolism contribute to the development of heart dysfunction, and how optimization of energy metabolism can be used to treat heart disease.  The topics covered include a discussion of the effects of myocardial ischemia, diabetes, obesity, hypertrophy, heart failure, and genetic disorders of mitochondrial oxidative metabolism on cardiac energetics.  The treatment of heart disease by optimizing energy metabolism is also discussed, which includes increasing overall energy production as well as increasing the efficiency of energy production and switching energy substrate preference of the heart. This book will be a valuable source of information to graduate students, postdoctoral fellows, and investigators in the field of experimental cardiology as well as biochemists, physiologists,pharmacologists, cardiologists, cardiovascular surgeons and other health professionals. 410 0$aAdvances in Biochemistry in Health and Disease,$x2512-2150 ;$v11 606 $aBiochemistry 606 $aBioinformatics 606 $aCardiology 606 $aBiochemistry 606 $aComputational and Systems Biology 606 $aCardiology 615 0$aBiochemistry. 615 0$aBioinformatics. 615 0$aCardiology. 615 14$aBiochemistry. 615 24$aComputational and Systems Biology. 615 24$aCardiology. 676 $a612.173 676 $a616.1205 702 $aLopaschuk$b Gary D$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aDhalla$b Naranjan S.$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298350603321 996 $aCardiac Energy Metabolism in Health and Disease$92537304 997 $aUNINA