LEADER 01747nam0 22003973i 450 001 CFI0179340 005 20251003044130.0 010 $a8814021090 100 $a20140530d1989 ||||0itac50 ba 101 | $aita 102 $ait 181 1$6z01$ai $bxxxe 182 1$6z01$an 200 1 $aˆLa ‰programmazione nelle pubbliche amministrazioni$elinee evolutive$fPaola Miolo Vitali, Luca Anselmi 210 $aMilano$cA. Giuffrè$d1989 215 $aX, 99 p.$d25 cm. 606 $aAmministrazione pubblica$xOrganizzazione$2FIR$3CFIC016683$9E 676 $a350$9AMMINISTRAZIONE PUBBLICA E SCIENZA MILITARE$v14 676 $a351.72$9Amministrazioni centrali. Gestione finanziaria$v12 696 $aPubblica amministrazione$aOrgani della pubblica amministrazione$aOrgani ordinari$aOrganizzazione 699 $aAmministrazione pubblica$yPubblica amministrazione 699 $aAmministrazione pubblica$yOrgani della pubblica amministrazione 699 $aAmministrazione pubblica$zOrgani ordinari 699 $aOrganizzazione$zOrganizzazione 700 1$aMiolo Vitali$b, Paola$3BVEV008631$4070$0106284 701 1$aAnselmi$b, Luca$3CFIV055481$4070$0115256 790 1$aVitali Miolo$b, Paola$3BVEV008632$zMiolo Vitali, Paola 790 1$aVitali Miolo$b, Paola$3BVEV008632$zMiolo Vitali, Paola 801 3$aIT$bIT-000000$c20140530 850 $aIT-BN0095 901 $bNAP 01$cGUERRAZZI $n$ 912 $aCFI0179340 950 0$aBiblioteca Centralizzata di Ateneo$c1 v.$d 01GUERRAZZI C 0294$e 0101 0000103325 VMA 1 v.$fA $h20091210$i20091210 977 $a 01 996 $aProgrammazione nelle pubbliche amministrazioni$962888 997 $aUNISANNIO LEADER 04535nam 22007095 450 001 9910298349903321 005 20251113211601.0 010 $a1-4939-0974-6 024 7 $a10.1007/978-1-4939-0974-2 035 $a(CKB)3710000000248745 035 $a(EBL)1964970 035 $a(OCoLC)891646612 035 $a(SSID)ssj0001353653 035 $a(PQKBManifestationID)11867741 035 $a(PQKBTitleCode)TC0001353653 035 $a(PQKBWorkID)11315598 035 $a(PQKB)10115807 035 $a(MiAaPQ)EBC1964970 035 $a(DE-He213)978-1-4939-0974-2 035 $a(PPN)181347008 035 $a(EXLCZ)993710000000248745 100 $a20140926d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aPathological Potential of Neuroglia $ePossible New Targets for Medical Intervention /$fedited by Vladimir Parpura, Alexei Verkhratsky 205 $a1st ed. 2014. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2014. 215 $a1 online resource (546 p.) 300 $aDescription based upon print version of record. 311 08$a1-4939-0973-8 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aGeneral Pathophysiology of Neuroglia: Neurological and Psychiatric Disorders as Gliopathies -- Ionic Signaling in Physiology and Pathophysiology of Astroglia -- Pathophysiology of Vesicle Dynamics in Astrocytes -- Glial Glutamate and Metabolic Transporters as a Target for Neurodegenerative Therapy and Biomarkers -- Alexander Disease and Astrotherapeutics -- Role of Astrocytes in Central Nervous System Traum -- Astroglial and Neuronal Integrity During Cortical Spreading Depolarization -- Crucial role for astrocytes in epilepsy -- Microglial Biology in Neuroinflammatory Disease: Pharmaco-industrial Approach to Target Validation -- The Role of Astrocytes in Huntington's Disease -- Amyotrophic Lateral Sclerosis: A Glial Perspective -- Complex and Associated Astroglial and Microglial Changes during the Progression of Alzheimer´s Disease -- Possible Therapeutic Targets in Microglia -- Novel Therapeutic Approaches to Malignant Gliomas -- Hepatic encephalopathy: A Primary Neurogliopathy -- Astroglia and Severe Mental Illness: A Role for Glutamate Microdomains -- Emerging Roles for Glial Pathology in Addiction -- Astroglial Connexins as Elements of Sleep-wake Cycle Regulation and Dysfunction -- Experimental Treatment of Acquired and Inherited Neuropathies -- Satellite glial cells as target for chronic pain therapy -- Enteric Glial Cells: Implications in Gut Pathology. 330 $aPathophysiological states, neurological and psychiatric diseases are almost universally considered from the neurocentric point of view, with neurons being the principal cellular element of pathological process. The brain homeostasis, which lies at the fulcrum of healthy brain function, the compromise of which invariably results in dysfunction/disease, however, is entirely controlled by neuroglia. It is becoming clear that neuroglial cells are involved in various aspects of initiation, progression and resolution of neuropathology.  In this book we aim to integrate the body of information that has accumulated in recent years revealing the active role of glia in such pathophysiological processes.  Understanding roles of glial cells in pathology will provide new targets for medical intervention and aide the development of much needed therapeutics. This book will be particularly useful for researchers, students, physicians and psychotherapists working in the field of neurobiology, neurology and psychiatry. 606 $aNeurosciences 606 $aNeurochemistry 606 $aNeurology 606 $aPsychiatry 606 $aNeuroscience 606 $aNeurochemistry 606 $aNeurology 606 $aPsychiatry 615 0$aNeurosciences. 615 0$aNeurochemistry. 615 0$aNeurology. 615 0$aPsychiatry. 615 14$aNeuroscience. 615 24$aNeurochemistry. 615 24$aNeurology. 615 24$aPsychiatry. 676 $a610 676 $a612.8 676 $a612.8042 676 $a616.8 702 $aParpura$b Vladimir$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aVerkhratsky$b Alexei$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298349903321 996 $aPathological Potential of Neuroglia$92539483 997 $aUNINA