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024 7 $a10.1007/978-94-017-9382-7
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035   $a(DE-He213)978-94-017-9382-7
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100   $a20140909d2014      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aSynthetic Biology $eFrom iGEM to the Artificial Cell /$fby Manuel Porcar, Juli Peretó
205   $a1st ed. 2014.
210  1$aDordrecht :$cSpringer Netherlands :$cImprint: Springer,$d2014.
215   $a1 online resource (86 p.)
225 1 $aSpringerBriefs in Biochemistry and Molecular Biology,$x2211-9353 ;$v12
300   $aDescription based upon print version of record.
311   $a94-017-9381-6 
320   $aIncludes bibliographical references and indexes.
327   $aForeword by Michel Morange -- Preface -- 1 What is synthetic biology? -- 2 What was synthetic biology? -- 3 What is life? -- 4 Strategies for making life -- 5 Synthetic biology in action -- 6 The iGEM competition -- 7 Are we doing synthetic biology? Postface by Ricard Solé -- Onomastic index -- Subject index.
330   $aSynthetic Biology (SB) is a revolutionary discipline with a vast range of practical applications, but is SB research really based on engineering principles? Does it contributing to the artificial synthesis of life or does it utilise approaches sufficiently advanced to fall outside the scope of biotechnology or metabolic engineering? This volume reviews the development of SB and includes the major milestones of the discipline, the ?top-down? and ?bottom-up? approaches towards the construction of an artificial cell and the development of the ?iGEM? competition. We conclude that SB is an emerging field with extraordinary technological potential, but that most research projects actually are an extension of metabolic engineering since the complexity of living organisms, their tight dependence on evolution and our limited knowledge of the interactions between the molecules, actually make life difficult to engineer.
410  0$aSpringerBriefs in Biochemistry and Molecular Biology,$x2211-9353 ;$v12
606   $aMedicine
606   $aMicrobial genetics
606   $aMicrobial genomics
606   $aGenetic engineering
606   $aEntomology
606   $aComputer simulation
606   $aBiomedicine, general$3https://scigraph.springernature.com/ontologies/product-market-codes/B0000X
606   $aMicrobial Genetics and Genomics$3https://scigraph.springernature.com/ontologies/product-market-codes/L32010
606   $aGenetic Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/C12037
606   $aEntomology$3https://scigraph.springernature.com/ontologies/product-market-codes/L25090
606   $aSimulation and Modeling$3https://scigraph.springernature.com/ontologies/product-market-codes/I19000
615  0$aMedicine.
615  0$aMicrobial genetics.
615  0$aMicrobial genomics.
615  0$aGenetic engineering.
615  0$aEntomology.
615  0$aComputer simulation.
615 14$aBiomedicine, general.
615 24$aMicrobial Genetics and Genomics.
615 24$aGenetic Engineering.
615 24$aEntomology.
615 24$aSimulation and Modeling.
676   $a174.957
700   $aPorcar$b Manuel$4aut$4http://id.loc.gov/vocabulary/relators/aut$01058251
702   $aPeretó$b Juli$4aut$4http://id.loc.gov/vocabulary/relators/aut
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910298348003321
996   $aSynthetic Biology$92498405
997   $aUNINA