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010   $a3-319-09414-9
024 7 $a10.1007/978-3-319-09414-4
035   $a(CKB)3710000000239436
035   $a(EBL)1967197
035   $a(OCoLC)891655201
035   $a(SSID)ssj0001353636
035   $a(PQKBManifestationID)11868554
035   $a(PQKBTitleCode)TC0001353636
035   $a(PQKBWorkID)11317062
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035   $a(MiAaPQ)EBC1967197
035   $a(DE-He213)978-3-319-09414-4
035   $a(PPN)181350726
035   $a(EXLCZ)993710000000239436
100   $a20140915d2014      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aHepatocellular Carcinoma $eCellular and Molecular Mechanisms and Novel Therapeutic Strategies /$fby Rajagopal N. Aravalli, Clifford J. Steer
205   $a1st ed. 2014.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2014.
215   $a1 online resource (74 p.)
225 1 $aSpringerBriefs in Cancer Research,$x2194-1173
300   $aDescription based upon print version of record.
311   $a3-319-09413-0 
320   $aIncludes bibliographical references and index.
327   $aIntroduction -- Etiology -- Current diagnosis and treatment options for HCC -- Pathophysiology of HCC -- Molecular mechanisms of HCC -- Animal models of liver cancer -- Novel therapeutic strategies to combat HCC -- Conclusions.
330   $aThis book provides up-to-date information on the development and progression of hepatocellular carcinoma (HCC) with a review of the cellular and molecular mechanisms involved in the disease process. Recent research in HCC has led to significant progress in our understanding of the cellular processes and molecular mechanisms that occur during multi-stage events that lead to hepatocarcinogenesis. The emergence of micro RNAs and molecular targeted therapies have added a new dimension in our efforts to combat this deadly disease, Chapters include discussion and evaluation of current intervention strategies and therapeutic options and a focus on the novel approaches that are being pursued, such as micro-RNA based therapies and personalized medicine to treat liver cancer. This book will be of interest to basic and clinical researchers, as well as to drug developers.
410  0$aSpringerBriefs in Cancer Research,$x2194-1173
606   $aCancer research
606   $aOncology  
606   $aPharmaceutical technology
606   $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001
606   $aOncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33160
606   $aPharmaceutical Sciences/Technology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21010
615  0$aCancer research.
615  0$aOncology  .
615  0$aPharmaceutical technology.
615 14$aCancer Research.
615 24$aOncology.
615 24$aPharmaceutical Sciences/Technology.
676   $a610
676   $a614.5999
676   $a615.19
676   $a616994
700   $aAravalli$b Rajagopal N$4aut$4http://id.loc.gov/vocabulary/relators/aut$01064276
702   $aSteer$b Clifford J$4aut$4http://id.loc.gov/vocabulary/relators/aut
906   $aBOOK
912   $a9910298342503321
996   $aHepatocellular Carcinoma$92537259
997   $aUNINA