LEADER 04571nam 22007335 450 001 9910298340603321 005 20210705032614.0 010 $a3-319-11155-8 024 7 $a10.1007/978-3-319-11155-1 035 $a(CKB)3710000000261926 035 $a(EBL)1966006 035 $a(OCoLC)893107194 035 $a(SSID)ssj0001372154 035 $a(PQKBManifestationID)11802067 035 $a(PQKBTitleCode)TC0001372154 035 $a(PQKBWorkID)11302076 035 $a(PQKB)10573091 035 $a(MiAaPQ)EBC1966006 035 $a(DE-He213)978-3-319-11155-1 035 $a(PPN)18209863X 035 $a(EXLCZ)993710000000261926 100 $a20141008d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aInfluenza Pathogenesis and Control - Volume I$fedited by Richard W. Compans, Michael B. A. Oldstone 205 $a1st ed. 2014. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2014. 215 $a1 online resource (442 p.) 225 1 $aCurrent Topics in Microbiology and Immunology,$x0070-217X ;$v385 300 $aDescription based upon print version of record. 311 $a3-319-11154-X 320 $aIncludes bibliographical references and index. 327 $aThe Hemagglutinin - a Determinant of Pathogenicity -- Molecular determinants of pathogenicity in the polymerase complex -- Receptor binding properties of the influenza virus hemagglutinin as a determinant of host range -- Acid-induced membrane fusion by the hemagglutinin protein and its role in influenza virus biology -- Pandemic Preparedness and the Influenza Risk Assessment Tool (IRAT) -- Avian influenza virus transmission to mammals -- Transmission in the Guinea Pig Model -- Enhancement of influenza virus transmission by gene reassortment -- Swine and Influenza: A Challenge to One Health Research -- Influenza Pathobiology and Pathogenesis in Avian Species -- Molecular determinants of influenza virus pathogenesis in mice -- Mammalian models for the study of H7 virus pathogenesis and transmission -- Pathogenesis and vaccination of influenza A virus in swine -- Secondary Bacterial Infections in Influenza Virus Infection Pathogenesis -- Evolution and Ecology of Influenza A viruses -- Influenza A virus reassortment -- Antigenic Analyses of Highly Pathogenic Avian Influenza A Viruses. 330 $aThis two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, immunology, cell and molecular biology, and pathogenesis. Volume I provides overviews of the latest findings on molecular determinants of viral pathogenicity, virus entry and cell tropism, pandemic risk assessment, transmission and pathogenesis in animal species, viral evolution, ecology and antigenic variation, while Volume II focuses on the role of innate and adaptive immunity in pathogenesis, development of vaccines and antivirals.  . 410 0$aCurrent Topics in Microbiology and Immunology,$x0070-217X ;$v385 606 $aVirology 606 $aImmunology 606 $aInfectious diseases 606 $aHealth promotion 606 $aVirology$3https://scigraph.springernature.com/ontologies/product-market-codes/B22003 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aInfectious Diseases$3https://scigraph.springernature.com/ontologies/product-market-codes/H33096 606 $aHealth Promotion and Disease Prevention$3https://scigraph.springernature.com/ontologies/product-market-codes/H27010 615 0$aVirology. 615 0$aImmunology. 615 0$aInfectious diseases. 615 0$aHealth promotion. 615 14$aVirology. 615 24$aImmunology. 615 24$aInfectious Diseases. 615 24$aHealth Promotion and Disease Prevention. 676 $a610 676 $a613 676 $a614.44 676 $a616.9 702 $aCompans$b Richard W$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aOldstone$b Michael B. A$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298340603321 996 $aInfluenza Pathogenesis and Control - Volume I$92505306 997 $aUNINA