LEADER 00533ogm 2200169z- 450 001 9910867329903321 035 $a(CKB)5700000000532279 035 $a(EXLCZ)995700000000532279 100 $a20240702c2023uuuu -u- v 101 0 $aeng 200 10$aPrinciple of Angular Impulse and Momentum: Problem Solving 210 $cMyJoVE Corporation 517 $aPrinciple of Angular Impulse and Momentum 906 $aVIDEO 912 $a9910867329903321 996 $aPrinciple of Angular Impulse and Momentum: Problem Solving$94170300 997 $aUNINA LEADER 03521nam 22006855 450 001 9910298340403321 005 20200706053402.0 010 $a3-319-07827-5 024 7 $a10.1007/978-3-319-07827-4 035 $a(CKB)3710000000168229 035 $a(EBL)1783079 035 $a(SSID)ssj0001295382 035 $a(PQKBManifestationID)11843692 035 $a(PQKBTitleCode)TC0001295382 035 $a(PQKBWorkID)11336772 035 $a(PQKB)11661881 035 $a(MiAaPQ)EBC1783079 035 $a(DE-He213)978-3-319-07827-4 035 $a(PPN)179924508 035 $a(EXLCZ)993710000000168229 100 $a20140704d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 14$aThe UNC-53-mediated Interactome $eAnalysis of its Role in the Generation of the C. elegans Connectome /$fby Amita Pandey, Girdhar K. Pandey 205 $a1st ed. 2014. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2014. 215 $a1 online resource (91 p.) 225 1 $aSpringerBriefs in Neuroscience,$x2191-558X ;$v0 300 $aDescription based upon print version of record. 311 $a1-322-13697-1 311 $a3-319-07826-7 320 $aIncludes bibliographical references at the end of each chapters. 327 $a Introduction -- Guidance molecules required for growth cone migrations of cells and axons -- Mechanism for asymmetric localization of guidance receptors during growth cone migration and outgrowth -- Signaling pathways downstream of the guidance cues and receptors -- Functional characterization of adaptor protein UNC-53 during axon outgrowth and cell migration. 330 $aThis book gives an overview of various interactomes involved in dorsal ventral (DV) and anterior posterior (AP) guidance, their mechanisms of action, subcellular localizations, and functional roles. It will provide readers a better understanding of the development of the nervous system, which in turn will help to find cures to various neural and other disorders. In nematodes there are two types of guidance systems, including DV and AP guidance. The signaling process that guides the growth cones along the DV axis has remained intact in both vertebrates and invertebrates. The adaptor protein UNC-53 appears to play a part in migration along the AP axis in both worms and their human homologs. ?Neuron Navigators? (NAV) are also involved in nervous system development . 410 0$aSpringerBriefs in Neuroscience,$x2191-558X ;$v0 606 $aNeurosciences 606 $aNeurobiology 606 $aNeurology 606 $aNeurosciences$3https://scigraph.springernature.com/ontologies/product-market-codes/B18006 606 $aNeurobiology$3https://scigraph.springernature.com/ontologies/product-market-codes/L25066 606 $aNeurology$3https://scigraph.springernature.com/ontologies/product-market-codes/H36001 615 0$aNeurosciences. 615 0$aNeurobiology. 615 0$aNeurology. 615 14$aNeurosciences. 615 24$aNeurobiology. 615 24$aNeurology. 676 $a591.188 700 $aPandey$b Amita$4aut$4http://id.loc.gov/vocabulary/relators/aut$01062578 702 $aPandey$b Girdhar K$4aut$4http://id.loc.gov/vocabulary/relators/aut 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298340403321 996 $aThe UNC-53-mediated Interactome$92526758 997 $aUNINA