LEADER 05320nam 22006375 450 001 9910298340003321 005 20200706032548.0 010 $a3-319-06151-8 024 7 $a10.1007/978-3-319-06151-1 035 $a(CKB)3710000000187182 035 $a(EBL)1782901 035 $a(SSID)ssj0001295371 035 $a(PQKBManifestationID)11775072 035 $a(PQKBTitleCode)TC0001295371 035 $a(PQKBWorkID)11342406 035 $a(PQKB)10507478 035 $a(MiAaPQ)EBC1782901 035 $a(DE-He213)978-3-319-06151-1 035 $a(PPN)179923684 035 $a(EXLCZ)993710000000187182 100 $a20140708d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aPharma-Nutrition $eAn Overview /$fedited by Gert Folkerts, Johan Garssen 205 $a1st ed. 2014. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2014. 215 $a1 online resource (483 p.) 225 1 $aAAPS Advances in the Pharmaceutical Sciences Series,$x2210-7371 ;$v12 300 $aDescription based upon print version of record. 311 $a1-322-13505-3 311 $a3-319-06150-X 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $a1 Introductory Chapter -- 2 New Developments in Food Safety Assessment: Innovations in Food Allergy and Toxicological Safety Assessment -- 3 Bridging a Pharma-Like Innovation Gap in Medical Nutrition -- 4 Modulation of the Gut Ecosystem in Irritable Bowel Syndrome -- 5 The Role of Omega-6 and Omega-3 Fatty Acids in Inflammatory Bowel Disease -- 6 N-3 Polyunsaturated Fatty Acid and Neuroinflammation in Aging: Role in Cognition -- 7 Nutritional Programming of Immune Defense Against Infections in Early Life? -- 8 Impact on Non-Digestible Oligosaccharides on Gut Associated Lymphoid Tissue and Oral Tolerance Induction -- 9 The Endocannabinoid System: Molecular Connection between Nutrition and Pharmacology -- 10 Effects of Natural products on Pharmacokinetics and Pharmacodynamics of Drugs -- 11 Nutrition and Gastrointestinal Health as Modulators of Parkinson?s Disease -- 12 Eat to Heal: Natural Inducers of the Hem Oxygenase-1 System -- 13 Recent Developments in the Treatment of Cachexia -- 14 Individualized Tumor Therapy: Biomarkers and Possibilities for Targeted Therapy with Natural Products -- 15 Nutrition in Oncology: from Treating Cachexia to Targeting the Tumor -- 16 Nutraceuticals in Preventive Oncology: Chemical Biology and Translational Pharmaceutical Science -- 17 The Onset Of Eczema: Underlying Mechanisms -- 18 Cow?s Milk Allergy: Protein Hydrolysates or Amino Acid Formula -- 19 Allergen Avoidance Versus Tolerance Induction -- 20 Nutrition and Cognitive Decline in Older Persons: Bridging the Gap between Epidemiology and Intervention Studies -- 21 Nutraceutical Regulation of the Neuroimmunoendocrine Super System -- 22 Targeting (Gut)-Immune-Brain Axis with Pharmaceutical and Nutritional Concepts: Relevance for Mental and Neurological Disorders -- 23 Nutritional Approaches for Healthy Aging of the Brain and the Prevention of Neurodegenerative Disease. 330 $aThis volume examines the effects of natural products and functional/medical foods (nutritional programming) on disease management. It specifically focuses on diseases related to inflammation and immunity, cancer and cachexia, allergies, and brain and neuro/immune. As both pharmacologists and nutritionists are recognizing that the one disease/one target/one drug (or nutrient) concept will be less successful than in the past, this book aims to stress the importance of a multi-target approach versus a single-target approach. It also presents aspects of molecular characteristics of food ingredients toward clinical effectiveness and relevance.   The interest in food in health and disease has exploded in the past few years, and publications on the microbiome can be found in all major scientific journals and newspapers. A new concept uses functional foods hand in hand with standard pharmacological therapies, which can be conceptualized in the term ?pharma-nutrition.? With the complementary values of pharma and nutrition, scientists might be able to overcome the increased incidence worldwide of complex multi-factorial disorders, chronic and degenerative diseases in particular. 410 0$aAAPS Advances in the Pharmaceutical Sciences Series,$x2210-7371 ;$v12 606 $aPharmaceutical technology 606 $aFood?Biotechnology 606 $aPharmaceutical Sciences/Technology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21010 606 $aFood Science$3https://scigraph.springernature.com/ontologies/product-market-codes/C15001 615 0$aPharmaceutical technology. 615 0$aFood?Biotechnology. 615 14$aPharmaceutical Sciences/Technology. 615 24$aFood Science. 676 $a613.2 702 $aFolkerts$b Gert$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aGarssen$b Johan$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298340003321 996 $aPharma-Nutrition$92502167 997 $aUNINA