LEADER 04312nam 22007335 450 001 9910298339003321 005 20200706173850.0 010 $a3-642-55404-0 024 7 $a10.1007/978-3-642-55404-9 035 $a(CKB)3710000000129309 035 $a(EBL)1783335 035 $a(SSID)ssj0001268751 035 $a(PQKBManifestationID)11725665 035 $a(PQKBTitleCode)TC0001268751 035 $a(PQKBWorkID)11277249 035 $a(PQKB)11570359 035 $a(MiAaPQ)EBC1783335 035 $a(DE-He213)978-3-642-55404-9 035 $a(PPN)179766988 035 $a(EXLCZ)993710000000129309 100 $a20140613d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aCholera Outbreaks$b[electronic resource] /$fedited by G. Balakrish Nair, Yoshifumi Takeda 205 $a1st ed. 2014. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2014. 215 $a1 online resource (267 p.) 225 1 $aCurrent Topics in Microbiology and Immunology,$x0070-217X ;$v379 300 $aDescription based upon print version of record. 311 $a1-322-13966-0 311 $a3-642-55403-2 320 $aIncludes bibliographical references and index at the end of each chapters. 327 $aCholera Outbreaks in the Classical Biotype Era -- Cholera Outbreaks in the El Tor Biotype Era and the Impact of the New El Tor variants -- Cholera Outbreaks in India -- Cholera Outbreaks in South East Asia -- Cholera Outbreaks in Africa -- The Cholera Outbreak in Haiti: Where and How Did it Begin?- Role of Phages in the Epidemiology of Cholera -- Circulation and Transmission of Clones of Vibrio Cholerae During Cholera Outbreaks -- Modelling Cholera Outbreaks -- Genomic Science in Understanding Cholera Outbreaks and Evolution of Vibrio cholerae as a Human pathogen -- When, How and Where Can Oral Cholera Vaccines be Used to Interrupt Cholera Outbreaks?. 330 $aThe most feared attribute of the human pathogen Vibrio cholerae is its ability to cause outbreaks that spread like wildfire, completely overwhelming public health systems and causing widespread suffering and death. This volume starts with a description of the contrasting patterns of outbreaks caused by the classical and El Tor biotypes of V. cholerae. Subsequent chapters examine cholera outbreaks in detail, including possible sources of infection and molecular epidemiology on three different continents, the emergence of new clones through the bactericidal selection process of lytic cholera phages, the circulation and transmission of clones of the pathogen during outbreaks, and novel approaches to modeling cholera outbreaks. A further contribution deals with the application of the genomic sciences to trace the spread of cholera epidemics and how this information can be used to control cholera outbreaks. The book closes with an analysis of the potential use of killed oral cholera vaccines to stop the spread of cholera outbreaks. 410 0$aCurrent Topics in Microbiology and Immunology,$x0070-217X ;$v379 606 $aMedical microbiology 606 $aInfectious diseases 606 $aVaccines 606 $aEpidemiology 606 $aMedical Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B16003 606 $aInfectious Diseases$3https://scigraph.springernature.com/ontologies/product-market-codes/H33096 606 $aVaccine$3https://scigraph.springernature.com/ontologies/product-market-codes/B16010 606 $aEpidemiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H63000 615 0$aMedical microbiology. 615 0$aInfectious diseases. 615 0$aVaccines. 615 0$aEpidemiology. 615 14$aMedical Microbiology. 615 24$aInfectious Diseases. 615 24$aVaccine. 615 24$aEpidemiology. 676 $a616.932 702 $aNair$b G. Balakrish$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aTakeda$b Yoshifumi$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298339003321 996 $aCholera Outbreaks$92529042 997 $aUNINA