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010   $a1-4614-8444-8
024 7 $a10.1007/978-1-4614-8444-8
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035   $a(EBL)1592891
035   $a(OCoLC)864027127
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035   $a(PQKBTitleCode)TC0001049032
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035   $a(MiAaPQ)EBC1592891
035   $a(DE-He213)978-1-4614-8444-8
035   $a(PPN)17609881X
035   $a(EXLCZ)992550000001151937
100   $a20131028d2014      u|             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aNon-coding RNAs and Cancer$b[electronic resource] /$fedited by Muller Fabbri
205   $a1st ed. 2014.
210  1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2014.
215   $a1 online resource (287 p.)
300   $aDescription based upon print version of record.
311   $a1-4614-8443-X 
320   $aIncludes bibliographical references and index.
327   $aIntroduction -- Biogenesis and Physiology of microRNAs.-Detecting non-coding RNA expression: from arrays to next generation sequencing -- MicroRNAs in Solid Tumors.-MicroRNAs in hematologic malignancies -- miRNAs as Cancer Biomarkers -- Unraveling the complex network of interactions between non-coding RNAs and epigenetics in cancer -- MicroRNA SNPs in Cancer -- Bioinformatics Approaches to the study of microRNAs -- Beyond miRNAs: role of other non-coding RNAs in cancer -- Translational Implications for non-coding RNA in Cancer -- Index.
330   $aThe discovery of microRNAs and its role as gene expression regulators in human carcinogenesis represents one of the most important scientific achievements of the last decade. More recently, other non-coding RNAs have been discovered and its implications in cancer are emerging as well, suggesting a broader than anticipated involvement of the non-coding genome in cancer. Moreover, completely new and unexpected functions for microRNAs are being revealed, leading to the identification of new anticancer molecular targets. This book represents a comprehensive guide on non-coding RNAs and cancer, spanning from its role as cancer biomarkers, to providing the most useful bioinformatic tools, to presenting some of the most relevant discoveries, which indicates how these fascinating molecules act as fine orchestrators of cancer biology.
606   $aCancer research
606   $aCell biology
606   $aBiochemistry
606   $aPosttranslational modification
606   $aGene expression
606   $aHuman genetics
606   $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001
606   $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008
606   $aBiochemistry, general$3https://scigraph.springernature.com/ontologies/product-market-codes/L14005
606   $aPosttranslational Modification$3https://scigraph.springernature.com/ontologies/product-market-codes/L14090
606   $aGene Expression$3https://scigraph.springernature.com/ontologies/product-market-codes/B12010
606   $aHuman Genetics$3https://scigraph.springernature.com/ontologies/product-market-codes/B12008
615  0$aCancer research.
615  0$aCell biology.
615  0$aBiochemistry.
615  0$aPosttranslational modification.
615  0$aGene expression.
615  0$aHuman genetics.
615 14$aCancer Research.
615 24$aCell Biology.
615 24$aBiochemistry, general.
615 24$aPosttranslational Modification.
615 24$aGene Expression.
615 24$aHuman Genetics.
676   $a571.6
676   $a572
676   $a572.6
676   $a599935
702   $aFabbri$b Muller$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910298337703321
996   $aNon-coding RNAs and Cancer$92521372
997   $aUNINA