LEADER 04110nam  22006975  450 
001 9910298337103321
005 20200706135124.0
010   $a1-4614-8220-8
024 7 $a10.1007/978-1-4614-8220-8
035   $a(CKB)3710000000094955
035   $a(EBL)1697687
035   $a(OCoLC)880448586
035   $a(SSID)ssj0001185946
035   $a(PQKBManifestationID)11746041
035   $a(PQKBTitleCode)TC0001185946
035   $a(PQKBWorkID)11229781
035   $a(PQKB)10675967
035   $a(MiAaPQ)EBC1697687
035   $a(DE-He213)978-1-4614-8220-8
035   $a(PPN)177823895
035   $a(EXLCZ)993710000000094955
100   $a20140329d2014      u|             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aNecrotic Cell Death$b[electronic resource] /$fedited by Han-Ming Shen, Peter Vandenabeele
205   $a1st ed. 2014.
210  1$aNew York, NY :$cSpringer New York :$cImprint: Humana,$d2014.
215   $a1 online resource (402 p.)
225 1 $aCell Death in Biology and Diseases,$x2625-2902
300   $aDescription based upon print version of record.
311   $a1-4614-8219-4 
320   $aIncludes bibliographical references at the end of each chapters and index.
327   $aNecrotic cell death at a glance: concept, mechanisms and biological functions -- Necroptosis: Alternative death modality under death receptors -- RIP1 and RIP3 in necrotic cell death -- PARP-mediated necrotic cell death -- Autophagic cell death, true or false? -- Oxidative stress and necrotic cell death -- Necrosis and DNA damage -- Lysosomes in necrotic cell death.- Necrotic cell death in development -- Necrotic cell death  in immunity -- Necrotic cell death in inflammation -- Necrotic cell death and cancer -- Necrotic cell death in ischemia reperfusion injury -- Necrostatin, a necrosis inhibitor as a therapeutic agent -- Necrotic cell death in model organisms (C. elegan) -- Methodology in studying necrotic cell death.
330   $aThis essential volume in the Cell Death in Biology and Diseases series presents comprehensive coverage of necrosis from recognized experts at leading academic and medical institutions around the world, thus keeping pace with the emerging research interest in necrosis. Starting with discussion of basic concepts and the molecular mechanisms of necrosis, this book looks first at the several forms of necrotic cell death that have been identified, including necroptosis, autophagic cell death, and PARP-mediated cell death.  As necrotic cell death is increasingly known to play a critical role in many physiological processes, the next chapters discuss its effect on metabolism, inflammation, immunity, and development. Necrotic cell death is closely implicated in human diseases like cancer so the next chapters examine its relevance to human diseases, and final chapters cover methodologies for measuring necrosis.
410  0$aCell Death in Biology and Diseases,$x2625-2902
606   $aCell cycle
606   $aApoptosis
606   $aOxidative stress
606   $aCell biology
606   $aCell Cycle Analysis$3https://scigraph.springernature.com/ontologies/product-market-codes/L16030
606   $aApoptosis$3https://scigraph.springernature.com/ontologies/product-market-codes/L16060
606   $aOxidative Stress$3https://scigraph.springernature.com/ontologies/product-market-codes/L16070
606   $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008
615  0$aCell cycle.
615  0$aApoptosis.
615  0$aOxidative stress.
615  0$aCell biology.
615 14$aCell Cycle Analysis.
615 24$aApoptosis.
615 24$aOxidative Stress.
615 24$aCell Biology.
676   $a571.936
702   $aShen$b Han-Ming$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aVandenabeele$b Peter$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910298337103321
996   $aNecrotic Cell Death$92536207
997   $aUNINA