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100   $a20141024d2014      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aHeat Shock Proteins and Whole Body Adaptation to Extreme Environments /$fby Michael B. Evgen'ev, David G. Garbuz, Olga G. Zatsepina
205   $a1st ed. 2014.
210  1$aDordrecht :$cSpringer Netherlands :$cImprint: Springer,$d2014.
215   $a1 online resource (233 p.)
300   $aDescription based upon print version of record.
311   $a94-017-9234-8 
320   $aIncludes bibliographical references and index.
327   $aIntroduction -- The discovery of heat shock response system and major groups of heat shock proteins -- Molecular functions of heat shock proteins -- Regulation of heat shock genes expression -- Heat shock proteins and adaptation to variable and extreme environments -- Different trends in the evolution of heat shock genes systems.- The role of mobile elements in the evolution and function of Hsps systems -- Fine tuning of the HSR in various organisms -- Experimental modulation of heat shock response -- Glossary.
330   $aFor many years, the authors have investigated the adaptive role of heat shock proteins (HSPs) in different animals, including the representatives of homothermic and poikilothermic organisms that inhabit regions with contrasting thermal conditions. The investigation of ecological and geographical variation in HSPs expression, begun by Evgen?ev and colleagues is now widespread. This book will summarize the data accumulated in the course of these studies and describe the general molecular mechanisms underlying the adaptation of various organisms to aggressive environments. They also concentrate on different evolutionary trends characteristic for HSP systems in the course of adaptation to fluctuating environmental conditions. In addition, the authors describe the peculiarities in the regulatory regions of heat shock genes necessary for fine tuning of these systems providing the adaptation to adverse conditions. Special emphasis is given to the role of mobile elements in the evolution and functioning of various groups of HSP genes. The book combines the results of field studies and laboratory analysis of stress genes systems.
606   $aMedicine
606   $aLife sciences
606   $aCytology
606   $aProteins
606   $aCell physiology
606   $aBiomedicine, general$3https://scigraph.springernature.com/ontologies/product-market-codes/B0000X
606   $aLife Sciences, general$3https://scigraph.springernature.com/ontologies/product-market-codes/L00004
606   $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008
606   $aProtein Science$3https://scigraph.springernature.com/ontologies/product-market-codes/L14040
606   $aCell Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/L33010
615  0$aMedicine.
615  0$aLife sciences.
615  0$aCytology.
615  0$aProteins.
615  0$aCell physiology.
615 14$aBiomedicine, general.
615 24$aLife Sciences, general.
615 24$aCell Biology.
615 24$aProtein Science.
615 24$aCell Physiology.
676   $a570
676   $a571.6
676   $a572.6
676   $a610
700   $aEvgen'ev$b Michael B$4aut$4http://id.loc.gov/vocabulary/relators/aut$01060392
702   $aGarbuz$b David G$4aut$4http://id.loc.gov/vocabulary/relators/aut
702   $aZatsepina$b Olga G$4aut$4http://id.loc.gov/vocabulary/relators/aut
906   $aBOOK
912   $a9910298336203321
996   $aHeat Shock Proteins and Whole Body Adaptation to Extreme Environments$92513123
997   $aUNINA