LEADER 01746nam 2200553Ia 450 001 9910452172303321 005 20200520144314.0 010 $a1-61761-353-3 035 $a(CKB)2550000001041694 035 $a(EBL)3018876 035 $a(SSID)ssj0000854381 035 $a(PQKBManifestationID)12419406 035 $a(PQKBTitleCode)TC0000854381 035 $a(PQKBWorkID)10902411 035 $a(PQKB)11122935 035 $a(MiAaPQ)EBC3018876 035 $a(Au-PeEL)EBL3018876 035 $a(CaPaEBR)ebr10661815 035 $a(OCoLC)923659485 035 $a(EXLCZ)992550000001041694 100 $a20100709d2010 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aNovel usage of erbium in optical communication systems$b[electronic resource] $efrom fundamentals to performance characteristics /$fShankar S. Pathmanathan and P.K. Choudhury 210 $aNew York $cNova Science$dc2010 215 $a1 online resource (67 p.) 225 1 $aMedia and communications 300 $aDescription based upon print version of record. 311 $a1-61728-955-8 320 $aIncludes bibliographical references and index. 410 0$aMedia and communications. 606 $aOptical fibers$xMaterials 606 $aErbium 608 $aElectronic books. 615 0$aOptical fibers$xMaterials. 615 0$aErbium. 676 $a621.382/75 700 $aPathmanathan$b Shankar S$0957181 701 $aChoudhury$b P. K$0957182 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910452172303321 996 $aNovel usage of erbium in optical communication systems$92168316 997 $aUNINA LEADER 03958nam 22006255 450 001 9910298332803321 005 20200705153832.0 010 $a3-7091-1806-9 024 7 $a10.1007/978-3-7091-1806-1 035 $a(CKB)3710000000248978 035 $a(EBL)1966152 035 $a(OCoLC)908084961 035 $a(SSID)ssj0001353663 035 $a(PQKBManifestationID)11768648 035 $a(PQKBTitleCode)TC0001353663 035 $a(PQKBWorkID)11316872 035 $a(PQKB)10768430 035 $a(MiAaPQ)EBC1966152 035 $a(DE-He213)978-3-7091-1806-1 035 $a(PPN)181347687 035 $a(EXLCZ)993710000000248978 100 $a20140922d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aRas Superfamily Small G Proteins: Biology and Mechanisms 1 $eGeneral Features, Signaling /$fedited by Alfred Wittinghofer 205 $a1st ed. 2014. 210 1$aVienna :$cSpringer Vienna :$cImprint: Springer,$d2014. 215 $a1 online resource (447 p.) 300 $aDescription based upon print version of record. 311 $a3-7091-1805-0 320 $aIncludes bibliographical references and index at the end of each chapters. 327 $aEvolution of the Ras Superfamily of GTPases -- The structure of the G domain of the Ras superfamily -- GEFs and GAPs: Mechanisms and Structures -- Bacterial protein toxins acting on small GTPases -- Posttranslational modifications of small G proteins -- Targeting the Raf-MEK-ERK Mitogen-Activates Protein Kinase Cascade for the Treatment of RAS Mutant Cancers -- RAS Genes and Cancer -- The Spatial Organization of Ras Signaling -- Ras Nanoclusters -- Mouse Models of Ras induced Tumors and Developmental Disorders -- Rap signaling -- The coordinated biology and signaling partners of Ral G-proteins -- Structure and Function of the mTOR Activator Rheb -- Classical Rho proteins: Biochemistry of molecular switch function and regulation -- Atypical Rho family members -- Molecular Structures, Cellular Functions and Physiological Roles of Rho Effectors -- Principles driving the spatial organization of Rho GTPase signaling at synapses -- Rho GTPases in Cancer. 330 $aThis first of two volumes provides a general overview of the genetics, structure, mechanism and regulation of the Ras superfamily proteins and describes in detail the signaling pathways and processes regulated by specific members of this family. The focus of this first volume is on the Rho and Ras subfamily of small G proteins. Renowned scientists provide insights into the biochemistry of the classical and non-classical small G-protein family members, their spatio-temporal regulation, their effectors and their roles in health and disease. Together with Volume 2, this book provides a comprehensive and state-of-the-art work on small G-proteins (GTPases). It is intended for graduates and professors in biochemistry and cell biology already working on small G-proteins (small GTPases), but also offers an extremely valuable resource for those readers who are new to the field. 606 $aCytology 606 $aProteins 606 $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008 606 $aProtein Science$3https://scigraph.springernature.com/ontologies/product-market-codes/L14040 606 $aProtein Structure$3https://scigraph.springernature.com/ontologies/product-market-codes/L14050 615 0$aCytology. 615 0$aProteins. 615 14$aCell Biology. 615 24$aProtein Science. 615 24$aProtein Structure. 676 $a570 676 $a571.6 676 $a572.6 676 $a572633 702 $aWittinghofer$b Alfred$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298332803321 996 $aRas Superfamily Small G Proteins: Biology and Mechanisms 1$92513120 997 $aUNINA