LEADER 01008nam0-22003491i-450- 001 990003090560403321 010 $a2-11-002868-8 035 $a000309056 035 $aFED01000309056 035 $a(Aleph)000309056FED01 035 $a000309056 100 $a20000920d1992----km-y0itay50------ba 101 0 $aita 102 $aIT 200 1 $a<>habitat du futur$eDéfis et prospectives pour le prochain quart de siècle$fAnne Cancellieri$gPréface de Michel Giraud. 210 $aParis$cLa documentation française$d1992. 215 $a484 p.$d24 cm 610 0 $aEconomia del territorio$aAspetti ambientali 610 0 $aRisorse naturali 676 $aF/3.110 676 $aH/0.1 676 $aH/0.2 700 1$aCancellieri,$bAnne$0123403 702 1$aGiraud,$bMichel 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990003090560403321 952 $aF/3.110 CAN$b12301$fSES 959 $aSES 996 $aHabitat du futur$9459409 997 $aUNINA DB $aING01 LEADER 04091nam 22006255 450 001 9910298331503321 005 20251008002633.0 010 $a1-4939-1167-8 024 7 $a10.1007/978-1-4939-1167-7 035 $a(CKB)3710000000280718 035 $a(EBL)1968160 035 $a(OCoLC)898497521 035 $a(SSID)ssj0001385854 035 $a(PQKBManifestationID)11818636 035 $a(PQKBTitleCode)TC0001385854 035 $a(PQKBWorkID)11358699 035 $a(PQKB)10140062 035 $a(MiAaPQ)EBC1968160 035 $a(DE-He213)978-1-4939-1167-7 035 $z(PPN)258857633 035 $a(PPN)183097629 035 $a(EXLCZ)993710000000280718 100 $a20141111d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aNicotinic Receptors /$fedited by Robin A.J. Lester 205 $a1st ed. 2014. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Humana,$d2014. 215 $a1 online resource (468 p.) 225 1 $aThe Receptors,$x1048-6909 ;$v26 300 $aDescription based upon print version of record. 311 08$a1-4939-1166-X 320 $aIncludes bibliographical references. 327 $aOn the Discovery of the Nicotinic Acetylcholine Receptor Channel -- Molecular Structure and Gating -- Molecular Underpinnings of Neuronal Nicotinic Acetylcholine Receptor Expression -- Presynaptic Nicotinic Receptors: Subtypes and Function -- Functional Distribution and Regulation of Neuronal Nicotinic Acetylcholine Receptors in the Mammalian Brain -- Nicotinic Signaling in Development -- Presynaptic Nicotinic Acetylcholine Receptors & The Modulation Of Circuit Excitability -- Autonomic Nervous System Transmission -- Nicotinic Receptors in the Spinal Cord -- Slow Synaptic Transmission in the Central Nervous System -- The Effects of Nicotine on Learning and Memory -- Nicotinic Receptors as Targets for Novel Analgesics and Anti-Inflammatory Drugs -- Nicotinic Acetylcholine Receptors and the Roles of the Alpha7 Subunit -- Role of Central Serotonin Receptors in Nicotine Addiction -- Neuronal Nicotinic Acetylcholine Receptors in Reward and Addiction -- Genetic Contributions of the ?5 Nicotinic Receptor Subunit to Smoking Behavior -- Smoking?Related Genes and Functional Consequences -- Nicotinic Acetylcholine Receptors Along the Habenulo-Interpeduncular Pathway: Roles in Nicotine Withdrawal and Other Aversive Aspects -- Nicotinic Acetylcholine Receptors in Alzheimer?s and Parkinson?s Disease -- Nicotinic Receptors and Mental Illness -- Current & Future Trends in Drug Discovery and Development Related to Nicotinic Receptors. 330 $aA comprehensive overview of nicotinic receptors that addresses their history from crystal structure to behavior as well as their implications in disease and potential as therapeutic targets. It includes background information on all subtypes of nicotinic receptors, the most recent information on the distribution throughout the nervous system, and discussion of their implications in learning and memory, addiction, and neurological and psychiatric disease such as Alzheimer's and Parkinson's. Takes advantage of several recent developments in the fields of optogenetics, viral expression, and gene analysis to focus on current knowledge on the functional aspects of nicotinic receptors. 410 0$aThe Receptors,$x1048-6909 ;$v26 606 $aNeurosciences 606 $aNeurochemistry 606 $aNeurosciences$3https://scigraph.springernature.com/ontologies/product-market-codes/B18006 606 $aNeurochemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/B18010 615 0$aNeurosciences. 615 0$aNeurochemistry. 615 14$aNeurosciences. 615 24$aNeurochemistry. 676 $a610 676 $a612.8 676 $a612.8042 702 $aLester$b Robin A. J$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298331503321 996 $aNicotinic Receptors$92522649 997 $aUNINA