LEADER 01048nam a2200277 i 4500 001 991004368938307536 005 20250219121426.0 008 250219s1990 it er 001 0 ita d 020 $a8842035033 040 $aBibl. Dip.le Aggr. Scienze Giuridiche - Sez. Studi Giuridici$bita$cSocioculturale Scs 041 0 $aita 082 04$a945.09$223. 100 1 $aSalvemini, Gaetano$d<1873-1957>$0342619 245 10$aSocialismo riformismo democrazia :$bantologia di scritti politici, civili, autobiografici /$cGaetano Salvemini ; a cura di Enzo Tagliacozzo e Sergio Bucchi 260 $aRoma [etc.] :$bLaterza,$c1990 300 $aLXXIV, 349 p. ;$c21 cm 490 1 $aCollezione di studi meridionali 650 4$aSocialismo$zItalia$y1860-1946 650 4$aRiformismo$zItalia$y1860-1946 650 4$aDemocrazia$zItalia$y1860-1946 700 1 $aTagliacozzo, Enzo 700 1 $aBucchi, Sergio 830 0$aCollezione di studi meridionali 912 $a991004368938307536 996 $aSocialismo riformismo democrazia$91429576 997 $aUNISALENTO LEADER 04696nam 22006375 450 001 9910298331103321 005 20200703025311.0 010 $a3-7091-1788-7 024 7 $a10.1007/978-3-7091-1788-0 035 $a(CKB)3710000000205431 035 $a(EBL)1783648 035 $a(OCoLC)892239417 035 $a(SSID)ssj0001295364 035 $a(PQKBManifestationID)11857556 035 $a(PQKBTitleCode)TC0001295364 035 $a(PQKBWorkID)11337102 035 $a(PQKB)10486781 035 $a(MiAaPQ)EBC1783648 035 $a(DE-He213)978-3-7091-1788-0 035 $a(PPN)179921800 035 $a(EXLCZ)993710000000205431 100 $a20140723d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aMolecular Machines Involved in Peroxisome Biogenesis and Maintenance /$fedited by Cecile Brocard, Andreas Hartig 205 $a1st ed. 2014. 210 1$aVienna :$cSpringer Vienna :$cImprint: Springer,$d2014. 215 $a1 online resource (540 p.) 300 $aDescription based upon print version of record. 311 $a3-7091-1787-9 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aPeroxisome biogenesis and function: History and Discovery of peroxins -- Human cell lines to study peroxisome biogenesis.- Mouse models to study peroxisome biogenesis -- Metabolic interaction between peroxisome and Mitochondria -- Peroxisomal Diseases:The Zellweger spectrum -- Molecular basis -- PEX11beta -- Peroxisome morphology in pathologies -- Other peroxisome-related disorders -- New technologies applied to study peroxisomes: Bioinformatics -- Imaging in plant and peroxules -- Tools to study peroxisomes as signaling platform: oxidative stress studies and antiviral innate immunity -- Proteomic approach. Protein transport across the peroxisomal membrane: The matrix protein import complex in yeast -- Protein transport in plant peroxisomes -- Concept Exportomer -- Factors involved in ubiquitination/deubiquitination of PEX5 -- Peroxisome dynamics: Trafficking of the peroxisome biogenesis factor PEX3 through the ER -- Role of PEX3 and PEX19 in peroxisome membrane biogenesis -- Vesicles, reticulon and ER-to-peroxisome contact sites -- Pex11 proteins and their alpha-helix -- Molecular complex coordinating peroxisome morphogenesis -- Dynamin-related proteins. Specific degradation through pexophagy: Principle of selective organelle degradation: Factors involved in pexophagy in the yeast Pichia pastoris. 330 $aIn eukaryotes, lipid metabolism requires the function of peroxisomes. These multitasking organelles are also part of species-specific pathways such as the glyoxylate cycle in yeast and plants or the synthesis of ether lipid in mammals. Proteins required for the biogenesis of peroxisomes typically assemble in large molecular complexes, which participate in membrane formation, protein transport, peroxisome duplication and - inheritance during cell division. Peroxisomal function is essential for life. Mutations in PEX genes, encoding for biogenesis factors, are often associated with lethal disorders. The association of peroxisomes with other organelles suggests an extensive participation in organellar crosstalk. This book represents a state-of-the-art review in the field of peroxisome research encompassing the cell and molecular biology of peroxisome biogenesis and its diseases, the protein complexes involved in this process and the modern technologies applied to study them. The book is intended for graduate students, researchers and lecturers in biochemistry, molecular and cell biology with a biomedical background. 606 $aCytology 606 $aBiology?Technique 606 $aCell membranes 606 $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008 606 $aBiological Techniques$3https://scigraph.springernature.com/ontologies/product-market-codes/L28000 606 $aMembrane Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16050 615 0$aCytology. 615 0$aBiology?Technique. 615 0$aCell membranes. 615 14$aCell Biology. 615 24$aBiological Techniques. 615 24$aMembrane Biology. 676 $a571.6 676 $a571.655 702 $aBrocard$b Cecile$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aHartig$b Andreas$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298331103321 996 $aMolecular Machines Involved in Peroxisome Biogenesis and Maintenance$92513118 997 $aUNINA