LEADER 00870nam0-22003131i-450- 001 990004384750403321 005 20080428124143.0 035 $a000438475 035 $aFED01000438475 035 $a(Aleph)000438475FED01 035 $a000438475 100 $a19990604d1974----km-y0itay50------ba 101 1 $aita$ceng 102 $aIT 105 $ay-------001yy 200 1 $aNuovo teatro americano$e1968-1973$fStefan Brecht 210 $aRoma$cBulzoni$d1974 215 $a366 p.$d22 cm 225 1 $aBiblioteca teatrale$v14 610 0 $aTeatro$aStati Uniti d'America$a1968-1973 676 $a792.0973$v20$zita 700 1$aBrecht,$bStefan$0389032 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990004384750403321 952 $a792.09 BRE 1$bBibl.46882$fFLFBC 959 $aFLFBC 996 $aNuovo teatro americano$9173750 997 $aUNINA LEADER 03564nam 22006615 450 001 9910298327403321 005 20200707003738.0 010 $a3-319-12766-7 024 7 $a10.1007/978-3-319-12766-8 035 $a(CKB)3710000000315948 035 $a(EBL)1965296 035 $a(OCoLC)900887006 035 $a(SSID)ssj0001407859 035 $a(PQKBManifestationID)11727540 035 $a(PQKBTitleCode)TC0001407859 035 $a(PQKBWorkID)11410059 035 $a(PQKB)10986971 035 $a(MiAaPQ)EBC1965296 035 $a(DE-He213)978-3-319-12766-8 035 $a(PPN)183149491 035 $a(EXLCZ)993710000000315948 100 $a20141212d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aMolecular Mechanisms Underpinning the Development of Obesity /$fedited by Clévio Nóbrega, Raquel Rodriguez-López 205 $a1st ed. 2014. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2014. 215 $a1 online resource (200 p.) 300 $aDescription based upon print version of record. 311 $a3-319-12765-9 320 $aIncludes bibliographical references at the end of each chapters. 327 $aChallenges in understanding development of obesity -- Monogenic forms of obesity -- Heterogeneous obesity syndromes: new strategies for diagnosis -- Genetic contribution: common forms of obesity -- The role of the GWAS identified FTO locus in regulating body size and composition -- Neural vulnerability factors that increase risk for weight gain: prevention and treatment implications -- Molecular mechanisms involved in the regulation of food intake -- Epigenetics of human obesity: a link between genetics and nutrition -- MicroRNAs in obesity and metabolism -- Obesity study: animal models -- From Homo obesus to Homo diabesus: neuroadipology insight -- Obesity and type 2 diabetes. 330 $aObesity is a multi-factorial disease, in which an excess of accumulated body fat can reach levels capable of affecting health. It results from an interplay between environmental factors, eating behavior, genes, epigenetics, and neuronal stimuli. The book provides a state-of-the-art revision about the molecular mechanisms underpinning the development of obesity, reviewing the current knowledge in areas like monogenic and polygenic obesity forms, while also providing an updated view of the emerging knowledge about epigenetics, nutrigenomics, and neuronal aspects that also contribute to obesity. 606 $aHuman genetics 606 $aBiochemistry 606 $aCytology 606 $aHuman Genetics$3https://scigraph.springernature.com/ontologies/product-market-codes/B12008 606 $aBiochemistry, general$3https://scigraph.springernature.com/ontologies/product-market-codes/L14005 606 $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008 615 0$aHuman genetics. 615 0$aBiochemistry. 615 0$aCytology. 615 14$aHuman Genetics. 615 24$aBiochemistry, general. 615 24$aCell Biology. 676 $a571.6 676 $a572 676 $a599935 676 $a610 702 $aNóbrega$b Clévio$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aRodriguez-López$b Raquel$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298327403321 996 $aMolecular Mechanisms Underpinning the Development of Obesity$92522647 997 $aUNINA