LEADER 04459nam 22007215 450 001 9910298323403321 005 20230926200843.0 010 $a94-007-7196-7 024 7 $a10.1007/978-94-007-7196-3 035 $a(CKB)3710000000026041 035 $a(EBL)1466382 035 $a(OCoLC)861080777 035 $a(SSID)ssj0001049052 035 $a(PQKBManifestationID)11623069 035 $a(PQKBTitleCode)TC0001049052 035 $a(PQKBWorkID)11017164 035 $a(PQKB)10293815 035 $a(MiAaPQ)EBC1466382 035 $a(DE-He213)978-94-007-7196-3 035 $a(PPN)176128700 035 $a(EXLCZ)993710000000026041 100 $a20131001d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aStem Cells and Cell Therapy /$fedited by Mohamed Al-Rubeai, Mariam Naciri 205 $a1st ed. 2014. 210 1$aDordrecht :$cSpringer Netherlands :$cImprint: Springer,$d2014. 215 $a1 online resource (194 p.) 225 1 $aCell Engineering,$x2542-9515 ;$v8 300 $aDescription based upon print version of record. 311 $a94-007-7195-9 320 $aIncludes bibliographical references and index. 327 $aUse of Human Embryonic Stem Cells in Therapy -- Human Neural Stem Cell-based Cell- and Gene-therapy for Neurological Diseases -- Vascular Stem Cell Therapy -- Bioprocessing of Human Pluripotent Stem Cells for Cell Therapy Applications -- Blood Cell Bioprocessing: The Haematopoietic System and Current Status of In-vitro Production of Red Blood Cells -- Bioprocessing Challenges Associated with the Purification of Cellular Therapies -- Separation Technologies for Stem Cell Bioprocessing. 330 $aWith the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues. The features of stem cells may provide treatment for some incurable diseases with some therapies are already in clinics, particularly those from adult stem cells. Some treatments will require large number of cells and may also require multiple doses, generating a growing demand for generating and processing large numbers of cells to meet the need of clinical applications. With this in mind, our aim is to provide a book on the subject of stem cells and cell therapy for researchers and students of cell biotechnology, bioengineering and bioproduction. This book is exceptional as it teaches researchers stem cells and cell therapy in that it covers the concepts and backgrounds necessary so that readers get a good understanding of the production of stem cells. The book covers three topics: The basics of stem cells and cell therapy, the use of stem cells for the treatment of human diseases, and stem cell processing. It includes chapters on neural and vascular stem vascular stem cell therapy, expansion engineering of embryonic stem cells, stem cell based production of blood cells and separation technologies for stem cells and cell therapy products. It is an informed and informative presentation of what modern research, science and engineering have learned about stem cells and their production and therapies. Addressing both the medical and production issues, this book is an invaluable contribution to having an academic and industrial understanding with respect to R&D and manufacturing of clinical grade stem cells. 410 0$aCell Engineering,$x2542-9515 ;$v8 606 $aMedicine$xResearch 606 $aBiology$xResearch 606 $aCytology 606 $aStem cells 606 $aCytology$xTechnique 606 $aBiomedical Research 606 $aCell Biology 606 $aStem Cell Biology 606 $aCytological Techniques 615 0$aMedicine$xResearch. 615 0$aBiology$xResearch. 615 0$aCytology. 615 0$aStem cells. 615 0$aCytology$xTechnique. 615 14$aBiomedical Research. 615 24$aCell Biology. 615 24$aStem Cell Biology. 615 24$aCytological Techniques. 676 $a616.02774 702 $aAl-Rubeai$b Mohamed$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aNaciri$b Mariam$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298323403321 996 $aStem Cells and Cell Therapy$92503026 997 $aUNINA