LEADER 04511nam 22007935 450 001 9910298322803321 005 20251116211513.0 010 $a3-0348-0828-3 024 7 $a10.1007/978-3-0348-0828-6 035 $a(CKB)2670000000548018 035 $a(EBL)1698504 035 $a(OCoLC)880551526 035 $a(SSID)ssj0001185880 035 $a(PQKBManifestationID)11688229 035 $a(PQKBTitleCode)TC0001185880 035 $a(PQKBWorkID)11210665 035 $a(PQKB)11279732 035 $a(MiAaPQ)EBC1698504 035 $a(DE-He213)978-3-0348-0828-6 035 $a(PPN)177825413 035 $a(EXLCZ)992670000000548018 100 $a20140320d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aCapsaicin as a Therapeutic Molecule /$fedited by Omar M. E. Abdel-Salam 205 $a1st ed. 2014. 210 1$aBasel :$cSpringer Basel :$cImprint: Springer,$d2014. 215 $a1 online resource (325 p.) 225 1 $aProgress in Drug Research ;$v68 300 $aDescription based upon print version of record. 311 08$a3-0348-0827-5 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aCapsaicin and Sensory Neurones: a Historical Perspective -- Pharmacology of the Capsaicin Receptor, Transient Receptor Potential Vanilloid Type 1 Ion Channel -- TRPV1 in the Central Nervous System: Synaptic Plasticity, Function and Pharmacological Implications -- Topical Capsaicin Formulations in the Management of Neuropathic Pain -- Capsaicin-Based Therapies for Pain Control -- Intranasal Capsaicin in Management of Non-allergic (Vasomotor) Rhinitis -- Capsaicin as an Anti-obesity Drug -- The Potential Antitumour Effects of Capsaicin -- Capsaicin as New Orally Applicable Gastroprotective and Therapeutic Drug Alone or in Combination with Non-Steroidal Anti-inflammatory Drugs in Human Healthy Subjects and in Patients -- Calcitonin Gene-Related Peptide as Target of Capsaicin Receptor in the Gut -- Capsaicin for Osteoarthritis Pain -- The Role of Capsaicin in Dermatology -- Use of Vanilloids in Urologic Disorders. 330 $aThis volume provides an up-to-date account of the achievements pertaining to the application of capsaicin and capsaicin-like molecules in the therapy of various human ailments such as pain, non-allergic rhinitis, obesity, tumors, and gastrointestinal, dermatologic, and urologic disorders. It discusses the basic functions  of  the capsaicin receptor (TRPV1), its mechanisms of action, and its role in physiological and pathological processes. The text focuses on the most recent progress in the use of capsaicin and capsaicin-like molecules as a therapeutic agent and highlights potential pharmaceutical implications of further TRPV1 research. The chapters are written by noted experts in their fields of endeavor. This book offers both clinicians and researchers valuable resource and reference material  on the subject that will stimulate future research. 410 0$aProgress in Drug Research,$x0071-786X ;$v68 606 $aPharmacology 606 $aPain medicine 606 $aOncology 606 $aUrology 606 $aDermatology 606 $aAllergy 606 $aPharmacology/Toxicology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21007 606 $aPain Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H47003 606 $aOncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33160 606 $aUrology$3https://scigraph.springernature.com/ontologies/product-market-codes/H62002 606 $aDermatology$3https://scigraph.springernature.com/ontologies/product-market-codes/H1900X 606 $aAllergology$3https://scigraph.springernature.com/ontologies/product-market-codes/H11009 615 0$aPharmacology. 615 0$aPain medicine. 615 0$aOncology. 615 0$aUrology. 615 0$aDermatology. 615 0$aAllergy. 615 14$aPharmacology/Toxicology. 615 24$aPain Medicine. 615 24$aOncology. 615 24$aUrology. 615 24$aDermatology. 615 24$aAllergology. 676 $a615.783 676 $a615.783 702 $aAbdel-Salam$b Omar M. E.$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298322803321 996 $aCapsaicin as a Therapeutic Molecule$92503025 997 $aUNINA