LEADER 05157nam 22008535 450 001 9910298322703321 005 20200703161352.0 010 $a3-319-03035-3 024 7 $a10.1007/978-3-319-03035-7 035 $a(CKB)3710000000074661 035 $a(EBL)1592371 035 $a(OCoLC)868901136 035 $a(SSID)ssj0001066617 035 $a(PQKBManifestationID)11630030 035 $a(PQKBTitleCode)TC0001066617 035 $a(PQKBWorkID)11068395 035 $a(PQKB)11701317 035 $a(MiAaPQ)EBC1592371 035 $a(DE-He213)978-3-319-03035-7 035 $a(PPN)176107371 035 $a(EXLCZ)993710000000074661 100 $a20131118d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aHigh-Performance In-Memory Genome Data Analysis $eHow In-Memory Database Technology Accelerates Personalized Medicine /$fedited by Hasso Plattner, Matthieu-P. Schapranow 205 $a1st ed. 2014. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2014. 215 $a1 online resource (239 p.) 225 1 $aIn-Memory Data Management Research,$x2196-8055 300 $aDescription based upon print version of record. 311 $a3-319-03034-5 320 $aIncludes bibliographical references and index. 327 $a1. Innovations for Personalized Medicine -- 2. Modeling Genome Data Processing Pipelines -- 3. Scheduling and Execution of Genome Data processing Pipelines -- 4. Exchanging Medical Knowledge -- 5. Billing Processes in Personalized Medicine -- 6. Real-time Analysis of Patient Cohorts -- 7. Ad-hoc Analysis of Genetic Pathways -- 8. Combined Search in Structured and Unstructured Medical Data -- Real-time Collaboration in the Course of Personalized Medicine. 330 $a Recent achievements in hardware and software developments have enabled the introduction of a revolutionary technology: in-memory data management. This technology supports the flexible and extremely fast analysis of massive amounts of data, such as diagnoses, therapies, and human genome data. This book shares the latest research results of applying in-memory data management to personalized medicine, changing it from computational possibility to clinical reality. The authors provide details on innovative approaches to enabling the processing, combination, and analysis of relevant data in real-time. The book bridges the gap between medical experts, such as physicians, clinicians, and biological researchers, and technology experts, such as software developers, database specialists, and statisticians. Topics covered in this book include - amongst others - modeling of genome data processing and analysis pipelines, high-throughput data processing, exchange of sensitive data and protection of intellectual property. Beyond that, it shares insights on research prototypes for the analysis of patient cohorts, topology analysis of biological pathways, and combined search in structured and unstructured medical data, and outlines completely new processes that have now become possible due to interactive data analyses. 410 0$aIn-Memory Data Management Research,$x2196-8055 606 $aBioinformatics  606 $aComputational biology  606 $aBioinformatics 606 $aInformation technology 606 $aBusiness?Data processing 606 $aStatistics  606 $aBiomathematics 606 $aHealth informatics 606 $aComputer Appl. in Life Sciences$3https://scigraph.springernature.com/ontologies/product-market-codes/L17004 606 $aComputational Biology/Bioinformatics$3https://scigraph.springernature.com/ontologies/product-market-codes/I23050 606 $aIT in Business$3https://scigraph.springernature.com/ontologies/product-market-codes/522000 606 $aStatistics and Computing/Statistics Programs$3https://scigraph.springernature.com/ontologies/product-market-codes/S12008 606 $aGenetics and Population Dynamics$3https://scigraph.springernature.com/ontologies/product-market-codes/M31010 606 $aHealth Informatics$3https://scigraph.springernature.com/ontologies/product-market-codes/H28009 615 0$aBioinformatics . 615 0$aComputational biology . 615 0$aBioinformatics. 615 0$aInformation technology. 615 0$aBusiness?Data processing. 615 0$aStatistics . 615 0$aBiomathematics. 615 0$aHealth informatics. 615 14$aComputer Appl. in Life Sciences. 615 24$aComputational Biology/Bioinformatics. 615 24$aIT in Business. 615 24$aStatistics and Computing/Statistics Programs. 615 24$aGenetics and Population Dynamics. 615 24$aHealth Informatics. 676 $a502.85 676 $a572.80285 702 $aPlattner$b Hasso$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aSchapranow$b Matthieu-P$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298322703321 996 $aHigh-Performance In-Memory Genome Data Analysis$92536195 997 $aUNINA