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010   $a94-017-8984-3
024 7 $a10.1007/978-94-017-8984-4
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035   $a(OCoLC)884585394
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035   $a(DE-He213)978-94-017-8984-4
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100   $a20140526d2014      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aMitochondria: The Anti- cancer Target for the Third Millennium /$fedited by Jiri Neuzil, Shazib Pervaiz, Simone Fulda
205   $a1st ed. 2014.
210  1$aDordrecht :$cSpringer Netherlands :$cImprint: Springer,$d2014.
215   $a1 online resource (387 p.)
300   $aDescription based upon print version of record.
311 08$a1-322-04414-7 
311 08$a94-017-8983-5 
320   $aIncludes bibliographical references at the end of each chapters and index.
327   $aPreface -- Mitochondrion: A novel center for cancer cell signalling -- Exploiting BH3 mimetics for cancer therapy -- Regulation of mitochondrial function by MicroRNA -- Mitochondrial complex II as a target for anti-cancer drugs -- Exploiting celecoxib in cancer therapy -- Activation of mitochondria-driven pathways by artemisinin and its derivatives -- Vitamin E analogues as prototypic mitochondria-targeting anti-cancer agents -- Targeting mitochondria of cancer cells: Mechanism and compounds -- Targets and strategies for the mitochondrial assault on cancer -- Emerging anti-cancer targets in mitochondria -- Relevance of mitochondrial functions and plasticity in tumor biology -- Crosstalk between p53 and mitochondrial metabolism -- Progression of cardiomyopathy in Friedreich?s ataxia, a mitochondrial disease -- Index.
330   $aMitochondria: The anti-cancer target for the third millennium is a collection of up-to-date contributions investigating the role of these organelles in human pathology, in particular cancer. Written by experts in the area of mitochondrial research, this book covers topics ranging from the basic science of the role of mitochondria in cellular homeostasis to more focused topics on the interaction with drugs, emerging targets in pathology and platforms for the development of novel drugs. The book will appeal to researchers interested in the role of mitochondria in pathology and in the latest discoveries in this area of research.
606   $aCancer$xResearch
606   $aOncology
606   $aMedicine
606   $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001
606   $aOncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33160
606   $aBiomedicine, general$3https://scigraph.springernature.com/ontologies/product-market-codes/B0000X
615  0$aCancer$xResearch.
615  0$aOncology.
615  0$aMedicine.
615 14$aCancer Research.
615 24$aOncology.
615 24$aBiomedicine, general.
676   $a616.994061
702   $aNeuzil$b Jiri$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aPervaiz$b Shazib$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aFulda$b Simone$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910298320103321
996   $aMitochondria: The Anti- cancer Target for the Third Millennium$92503021
997   $aUNINA