LEADER 04615nam 22007935 450 001 9910298310103321 005 20200702085359.0 010 $a3-642-39432-9 024 7 $a10.1007/978-3-642-39432-4 035 $a(CKB)3710000000074959 035 $a(EBL)1593147 035 $a(SSID)ssj0001066443 035 $a(PQKBManifestationID)11650327 035 $a(PQKBTitleCode)TC0001066443 035 $a(PQKBWorkID)11067234 035 $a(PQKB)11701605 035 $a(MiAaPQ)EBC1593147 035 $a(DE-He213)978-3-642-39432-4 035 $a(PPN)176113231 035 $a(EXLCZ)993710000000074959 100 $a20131129d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aHuman Fungal Pathogens /$fedited by Oliver Kurzai 205 $a2nd ed. 2014. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2014. 215 $a1 online resource (312 p.) 225 1 $aThe Mycota, A Comprehensive Treatise on Fungi as Experimental Systems for Basic and Applied Research ;$v12 300 $aDescription based upon print version of record. 311 $a3-642-39431-0 320 $aIncludes bibliographical references and index. 327 $aFrom Commensal to Pathogen: Candida albicans -- Aspergillus fumigatus: Saprotroph to Pathogen -- Systems Biology Approaches to Understand and Predict Fungal Virulence -- Receptor-Ligand Interactions in Fungal Infections -- Macrophages in the Immune Response against Cryptococcus -- T Cell Responses in Fungal Infections -- Molecular Mechanisms of Histoplasma Pathogenesis -- Visualizing Immune Responses in Fungal Infections ? Established and Novel Methods -- Mucosal Immunology in Candida albicans Infection -- Invasive Aspergillosis in the Intensive Care Unit -- Molecular Epidemiology of Pneumocystis Outbreaks -- Infections Caused by Mucorales -- Diagnostics of Fungal Infections -- Therapeutic Strategies in Fungal Infections -- Antifungal Pharmacokinetics. 330 $aWhereas plant and insect infections are commonly caused by fungi, only a small minority of the vast diversity of fungal species is pathogenic to humans. Despite this, fungal infections cause considerable morbidity and mortality worldwide. This volume is dedicated to the biology, clinical presentation and management of invasive fungal infections. Major pathogenic fungi are introduced by world-leading experts and the basic principles of fungal virulence are reviewed in the light of new results and experimental technologies that offer unprecedented insights into invasive infections caused by Aspergillus, Candida, Cryptococcus, Pneumocystis and Mucorales. In parallel, the clinical presentation of invasive fungal infections and current approaches to their diagnosis and treatment are summarized to provide an overview of human pathogenic fungi, linking pathogen biology to the clinical presentation of disease. 410 0$aThe Mycota, A Comprehensive Treatise on Fungi as Experimental Systems for Basic and Applied Research ;$v12 606 $aMedical microbiology 606 $aImmunology 606 $aAllergy 606 $aCytology 606 $aMicrobiology 606 $aMicrobial genetics 606 $aMicrobial genomics 606 $aMedical Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B16003 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aAllergology$3https://scigraph.springernature.com/ontologies/product-market-codes/H11009 606 $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008 606 $aEukaryotic Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/L23020 606 $aMicrobial Genetics and Genomics$3https://scigraph.springernature.com/ontologies/product-market-codes/L32010 615 0$aMedical microbiology. 615 0$aImmunology. 615 0$aAllergy. 615 0$aCytology. 615 0$aMicrobiology. 615 0$aMicrobial genetics. 615 0$aMicrobial genomics. 615 14$aMedical Microbiology. 615 24$aImmunology. 615 24$aAllergology. 615 24$aCell Biology. 615 24$aEukaryotic Microbiology. 615 24$aMicrobial Genetics and Genomics. 676 $a616.96901 702 $aKurzai$b Oliver$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298310103321 996 $aHuman Fungal Pathogens$92498378 997 $aUNINA