LEADER 03307nam 22006975 450 001 9910298304703321 005 20200701155823.0 010 $a3-642-40282-8 024 7 $a10.1007/978-3-642-40282-1 035 $a(CKB)3710000000074329 035 $a(EBL)1593174 035 $a(OCoLC)868915601 035 $a(SSID)ssj0001066502 035 $a(PQKBManifestationID)11583700 035 $a(PQKBTitleCode)TC0001066502 035 $a(PQKBWorkID)11068016 035 $a(PQKB)10269895 035 $a(MiAaPQ)EBC1593174 035 $a(DE-He213)978-3-642-40282-1 035 $a(PPN)176114467 035 $a(EXLCZ)993710000000074329 100 $a20131108d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aPathologies of Calcium Channels /$fedited by Norbert Weiss, Alexandra Koschak 205 $a1st ed. 2014. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2014. 215 $a1 online resource (725 p.) 300 $aIncludes index. 311 $a3-642-40281-X 327 $aPart I Pathologies of Voltage-Gated Calcium Channels -- Part II Pathologies of Transient Receptor Potential Channels -- Part III Pathologies of Ligand-Gated Calcium Channels. 330 $aCalcium ions represent Mother Nature?s ?ion-of-choice? for regulating fundamental physiological functions, as they initiate a new life at the time of fertilization and guide subsequent developmental and physiological functions of the human body. Calcium channels, which act as gated pathways for the movement of calcium ions across the membranes, play a central part in the initiation of calcium signals, and defects in calcium channel function have been found to result in a plethora of human diseases, referred to as the calcium channelopathies. Pathologies of Calcium Channels brings together leading international experts to discuss our current understanding of human diseases associated with the various calcium channels, from their molecular basis to potential future therapeutic targeting of calcium channels. 606 $aHuman physiology 606 $aProteins  606 $aNeurochemistry 606 $aInternal medicine 606 $aHuman Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B13004 606 $aReceptors$3https://scigraph.springernature.com/ontologies/product-market-codes/L14110 606 $aNeurochemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/B18010 606 $aInternal Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H33002 615 0$aHuman physiology. 615 0$aProteins . 615 0$aNeurochemistry. 615 0$aInternal medicine. 615 14$aHuman Physiology. 615 24$aReceptors. 615 24$aNeurochemistry. 615 24$aInternal Medicine. 676 $a572696 676 $a610 676 $a612 676 $a612.01524 702 $aWeiss$b Norbert$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aKoschak$b Alexandra$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298304703321 996 $aPathologies of Calcium Channels$92499307 997 $aUNINA