LEADER 04806nam 22006855 450 001 9910298303903321 005 20200704031521.0 010 $a1-4614-9569-5 024 7 $a10.1007/978-1-4614-9569-7 035 $a(CKB)2560000000148534 035 $a(EBL)1730867 035 $a(OCoLC)902412173 035 $a(SSID)ssj0001199613 035 $a(PQKBManifestationID)11690854 035 $a(PQKBTitleCode)TC0001199613 035 $a(PQKBWorkID)11204861 035 $a(PQKB)11788534 035 $a(MiAaPQ)EBC1730867 035 $a(DE-He213)978-1-4614-9569-7 035 $z(PPN)258858567 035 $a(PPN)178321761 035 $a(EXLCZ)992560000000148534 100 $a20140416d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aAdult Stem Cells /$fedited by Kursad Turksen 205 $a2nd ed. 2014. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Humana,$d2014. 215 $a1 online resource (433 p.) 225 1 $aStem Cell Biology and Regenerative Medicine,$x2196-8985 300 $aDescription based upon print version of record. 311 $a1-4614-9568-7 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aSignaling Pathways Maintaining Stemness in Adult Hematopoietic Stem Cells -- The Adult Stem Cell Niche -- Adult Stem Cells: Adult Skeletal Muscle Stem Cells -- Adult Cardiac Stem Cells: Identity, Location and Potential -- Adult Pituitary Stem Cells -- Toward Translating Molecular Ear Development to Generate Hair Cells from Stem Cells -- Adult Human Corneal Epithelial Stem Cells -- Adult Stem Cells in Teeth -- Adult Mammary Stem Cells: Identity, Location and Functional Assays -- Adult Ovary Stem Cells -- Adult Prostate Stem Cells -- Adult Lung Stem Cells -- Adult Liver Stem Cells -- Lineage-committed Pancreatic Progenitors and Stem Cells -- Adult Stromal (Skeletal, Mesenchymal) Stem Cells -- Regeneration after Injury - Activation of Stem Cell Stress Response Pathways to Rapidly Repair Tissues -- Molecular and Endocrine Mechanisms Underlying the Stem Cell Theory of Aging. 330 $aAdult Stem Cells, second edition, takes a critical look at issues concerning the  developmental or differentiation potential for a variety of tissue types and for specific adult stem cell types. Since the first edition appeared a decade ago, our understanding of adult stem cells, and more specifically tissue-specific adult stem cells, has advanced tremendously. And an increased interest in regenerative medicine and potential stem cell applications  has driven a quest for better understanding of stem cell biology. In turn, this has spawned much activity on generation and utilization of more and better reagents to identify and isolate stem cells and stem cell-like subpopulations, and on assays elucidating their developmental or differentiation potential and functional integration with host tissues and organs. In this fully updated new edition, chapters cover topics ranging from signaling pathways maintaining stemness in hematopoietic cells to regeneration after injury and endocrine mechanisms underlying the stem cell theory of aging. Other chapters cover  stem cells by organ or system including pituitary, cardiac, epithelial, teeth, lung, ovary, prostate, liver, and many more.  Importantly, the authors of the chapters have not only summarized their successes, but have also summarized some of the difficulties that each particular field is still facing with respect to maximizing the utility of stem cells in clinical settings. Collectively, they impart both the excitement and challenges facing stem cell utilization for repair and regeneration  making this book essential reading for those involved in stem cell research as well as those involved in clinical assays. 410 0$aStem Cell Biology and Regenerative Medicine,$x2196-8985 606 $aStem cells 606 $aBiotechnology 606 $aCell biology 606 $aStem Cells$3https://scigraph.springernature.com/ontologies/product-market-codes/L16010 606 $aBiotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/C12002 606 $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008 615 0$aStem cells. 615 0$aBiotechnology. 615 0$aCell biology. 615 14$aStem Cells. 615 24$aBiotechnology. 615 24$aCell Biology. 676 $a571.8/35 702 $aTurksen$b Kursad$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298303903321 996 $aAdult stem cells$9990299 997 $aUNINA