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010   $a94-007-7624-1
024 7 $a10.1007/978-94-007-7624-1
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035   $a(OCoLC)902407086
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035   $a(DE-He213)978-94-007-7624-1
035   $a(PPN)176129790
035   $a(EXLCZ)993710000000058407
100   $a20131029d2014      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aCorynebacterium diphtheriae and Related Toxigenic Species $eGenomics, Pathogenicity and Applications /$fedited by Andreas Burkovski
205   $a1st ed. 2014.
210  1$aDordrecht :$cSpringer Netherlands :$cImprint: Springer,$d2014.
215   $a1 online resource (302 p.)
300   $aDescription based upon print version of record.
311   $a94-007-7623-3 
320   $aIncludes bibliographical references and index.
327   $aDiphtheria and Its Etiological Agents -- Corynebacterium diphtheriae, Corynebacterium ulcerans and Corynebacterium pseudotuberculosis - General Aspects -- Comparative Genomics and Pathogenicity Islands of Corynebacterium diphtheriae, Corynebacterium ulcerans and Corynebacterium pseudotuberculosis -- Corynephages: Infections of the Infectors -- Toxin Structure, Delivery and Action -- Iron Acquisition and Iron-Dependent Gene expression in Corynebacterium diphtheria -- Assembly and Function of Corynebacterium diphtheria -- Toxigenic Corynebacteria: Adhesion, Invasion and Host Response -- Detection Methods for Laboratory Diagnosis of Diphtheria -- Diphtheria Surveillance -- History of diphtheria Vaccine Development -- Antimicrobial Susceptibility and Treatment -- Sialidases of Corynebacteria and Their Biotechnological Application -- Molecular Genetic Tools for Research in Corynebacterium diphtheria -- Diphtheria Toxin Based Molecules as Therapeutic Approaches.
330   $aCorynebacterium diphtheriae is the classical etiological agent of diphtheria and the type strain of the genus Corynebacterium. While diphtheria of the respiratory tract became rare with the introduction of vaccination programs in industrialized countries, even today several thousand cases per year are reported to the World Health Organization. This shows that diphtheria is not completely eradicated and that reservoirs exist. The book summarizes the latest advances made in understanding C. diphtheriae and the closely related species Corynebacterium ulcerans and Corynebacterium pseudotuberculosis. Topics addressed are genomics of toxigenic corynebacteria, host-pathogen-interaction, detection, surveillance and treatment as well as application aspects.
606   $aMedical microbiology
606   $aBacteriology
606   $aEpidemiology
606   $aParasitology
606   $aMicrobial genetics
606   $aMicrobial genomics
606   $aMedical Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B16003
606   $aBacteriology$3https://scigraph.springernature.com/ontologies/product-market-codes/L23012
606   $aEpidemiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H63000
606   $aParasitology$3https://scigraph.springernature.com/ontologies/product-market-codes/B19002
606   $aMicrobial Genetics and Genomics$3https://scigraph.springernature.com/ontologies/product-market-codes/L32010
615  0$aMedical microbiology.
615  0$aBacteriology.
615  0$aEpidemiology.
615  0$aParasitology.
615  0$aMicrobial genetics.
615  0$aMicrobial genomics.
615 14$aMedical Microbiology.
615 24$aBacteriology.
615 24$aEpidemiology.
615 24$aParasitology.
615 24$aMicrobial Genetics and Genomics.
676   $a579.135
702   $aBurkovski$b Andreas$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910298302003321
996   $aCorynebacterium diphtheriae and Related Toxigenic Species$92505629
997   $aUNINA