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010   $a3-319-13939-8
024 7 $a10.1007/978-3-319-13939-5
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035   $a(EBL)2095510
035   $a(SSID)ssj0001500691
035   $a(PQKBManifestationID)11967970
035   $a(PQKBTitleCode)TC0001500691
035   $a(PQKBWorkID)11535917
035   $a(PQKB)10309685
035   $a(DE-He213)978-3-319-13939-5
035   $a(MiAaPQ)EBC2095510
035   $a(PPN)186027729
035   $a(EXLCZ)993710000000412155
100   $a20150504d2015      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aToxicity and Autophagy in Neurodegenerative Disorders /$fedited by José M. Fuentes
205   $a1st ed. 2015.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015.
215   $a1 online resource (277 p.)
225 1 $aCurrent Topics in Neurotoxicity,$x2363-9563 ;$v9
300   $aDescription based upon print version of record.
311   $a3-319-13938-X 
320   $aIncludes bibliographical references at the end of each chapters and index.
327   $aRegulation of Autophagy In Health And Disease -- Role of Chaperone-Mediated Autophagy in Ageing and Neurodegeneration -- Interaction Between Mitochondria And Autophagy -- Dual role of autophagy in neurodegenerative diseases: The case of amyotrophic lateral sclerosis -- Autophagy pathways in Huntington?s disease -- Control of Autophagy in Parkinson?s Disease -- Autophagy in Alzheimer?s disease: a cleaning service out-of-order? -- Autophagy as a neuroprotective mechanism against 3-nitropropionic acid-induced cell death -- Paraquat: Molecular Mechanisms of Neurotoxicity and its Relation with Autophagy -- Agrochemicals-induced Dopaminergic Neurotoxicity:  Role of Mitochondria-mediated oxidative stress and Protein Clearance Mechanisms -- Molecular And Neurochemical Mechanisms Dopamine Oxidation To O-Quinones In Parkinson´S Disease Pathogenesis -- Exploring the Role of Autophagy in the Pathogenesis of Rotenone-Induced Toxicity.-  Autophagic pathology and calcium deregulation in neurodegeneration. .
330   $aComprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principal cellular pathways implicate in the clearance of these material and can serve as a neuroprotective mechanism. Topics include: the role of autophagy in the brain, the role of autophagy in the principal neurodegenerative disorders, and the mechanism by which different molecules cause neurotoxicity and the role autophagy plays.
410  0$aCurrent Topics in Neurotoxicity,$x2363-9563 ;$v9
606   $aNeurochemistry
606   $aNeurochemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/B18010
615  0$aNeurochemistry.
615 14$aNeurochemistry.
676   $a610
676   $a612.8042
702   $aFuentes$b José M$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910298299903321
996   $aToxicity and Autophagy in Neurodegenerative Disorders$92505627
997   $aUNINA