LEADER 03894nam 22006615 450 001 9910298294703321 005 20200704123340.0 010 $a3-319-09432-7 024 7 $a10.1007/978-3-319-09432-8 035 $a(CKB)3710000000262059 035 $a(EBL)1965380 035 $a(OCoLC)894114836 035 $a(SSID)ssj0001372151 035 $a(PQKBManifestationID)11787371 035 $a(PQKBTitleCode)TC0001372151 035 $a(PQKBWorkID)11301265 035 $a(PQKB)10733351 035 $a(DE-He213)978-3-319-09432-8 035 $a(MiAaPQ)EBC1965380 035 $z(PPN)258868902 035 $a(PPN)182093778 035 $a(EXLCZ)993710000000262059 100 $a20141016d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aHuman and Mosquito Lysozymes $eOld Molecules for New Approaches Against Malaria /$fedited by Mauro Prato 205 $a1st ed. 2015. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015. 215 $a1 online resource (113 p.) 300 $aDescription based upon print version of record. 311 $a3-319-09431-9 320 $aIncludes bibliographical references and index. 327 $aEtiopathogenesis and pathophysiology of malaria -- Malaria diagnosis, therapy, vaccines and vector control -- Lysozymes in the animal kingdom -- Role of lysozymes of Anopheles mosquitoes in Plasmodium development -- Effects of malaria products on human monocyte and neutrophil degranulation and lysozyme release -- Human lysozyme in malaria patients -- Beyond lysozyme. 330 $aMalaria remains an alarming emergency in developing countries. It is thus urgent to identify any parasite or host molecules that can serve as new affordable markers for early diagnosis of disease complications or as new targets for vector control. In this context, human and mosquito lysozymes are good candidate molecules, as their involvement in malaria has been recently reported by several independent groups. This book reviews the grounded knowledge on malaria etiology and physiopathology, as well as the current approaches for diagnosis, therapy, and vector control. In addition, the emerging evidence on the involvement of human and mosquito lysozymes in malaria from available experimental models and clinical studies is thoroughly discussed, as is the potential use of other antimicrobial peptides against malaria. Intriguingly, the contributors propose that old well-known molecules such as lysozymes might be used as new targets for cost-effective strategies to fight malaria. About the Editor Mauro Prato currently works as an Adjunct Professor of Biochemistry at the University of Torino, Italy. His research activity focuses on the involvement of proteolytic enzymes in malaria. His track-record includes 40 papers published by peer-reviewed journals, 1 book, 7 book chapters, 97 communications in well-established conferences, and 1 patent. 606 $aParasitology 606 $aMedical microbiology 606 $aImmunology 606 $aParasitology$3https://scigraph.springernature.com/ontologies/product-market-codes/B19002 606 $aMedical Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B16003 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 615 0$aParasitology. 615 0$aMedical microbiology. 615 0$aImmunology. 615 14$aParasitology. 615 24$aMedical Microbiology. 615 24$aImmunology. 676 $a610 676 $a616.9041 676 $a616.96 676 $a616079 702 $aPrato$b Mauro$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298294703321 996 $aHuman and Mosquito Lysozymes$92536146 997 $aUNINA