LEADER 04182nam 22006975 450 001 9910298292803321 005 20200630205345.0 010 $a1-4939-2389-7 024 7 $a10.1007/978-1-4939-2389-2 035 $a(CKB)3710000000414068 035 $a(EBL)2094245 035 $a(SSID)ssj0001500684 035 $a(PQKBManifestationID)11904543 035 $a(PQKBTitleCode)TC0001500684 035 $a(PQKBWorkID)11519888 035 $a(PQKB)10524492 035 $a(DE-He213)978-1-4939-2389-2 035 $a(MiAaPQ)EBC2094245 035 $a(PPN)186025491 035 $a(EXLCZ)993710000000414068 100 $a20150515d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aSomatic Genome Manipulation $eAdvances, Methods, and Applications /$fedited by Xiu-Qing Li, Danielle J. Donnelly, Thomas G. Jensen 205 $a1st ed. 2015. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2015. 215 $a1 online resource (378 p.) 300 $aDescription based upon print version of record. 311 $a1-4939-2388-9 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aDrug and Gene Electrotransfer in Cancer Therapy -- Targeted Porcine Genome Engineering with TALENs -- Somatic Gene Therapy using Viral Vectors: theoretical and clinical implications in relation to treatment of genetic conditions in humans -- Nonviral Gene Therapy ? The Challenge of Mobilizing DNA -- Human Stromal Stem Cell Therapy Using Gene Modified Cells -- Somatic Cell Nuclear Transfer and the Creation of Transgenic Large Animal Models -- Apomixis: The Asexual Formation of Seed -- Somatic Embryogenesis for Potato (Solanum tuberosum L.) Improvement -- Brassica Ogu-INRA Cytoplasmic Male Sterility: An Example of Successful Plant Somatic Fusion for Hybrid Seed Production -- Protoplast Technology in Genome Manipulation of Potato Through Somatic Cell Fusion -- Strategic RNA Silencing for Plant Viral Resistance -- Targeted Gene Mutation in Plants -- Mitochondrial Genetic Manipulation -- Laboratory Methods for Investigating Nuclear and Cytoplasmic Genomes and Transcriptome -- Bioinformatic approaches for analysis of gene direction, chromosome base composition, mRNA polyadenylation, and protein network. 330 $aThis book brings together previously fragmented information on new technologies in somatic genome manipulation. These technologies are developing quickly across a broad range of disciplines affecting humans and animals, plants, and microorganisms. This book represents the first attempt to assemble updated reviews, detailed protocols, and far-reaching applications in somatic genome manipulation. The chapters are written by experts on the topic with ready-to-use protocols that were originally developed or adapted from the literature in their laboratories. 606 $aPlant breeding 606 $aAnimal genetics 606 $aMicrobial genetics 606 $aMicrobial genomics 606 $aPlant Breeding/Biotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/L24060 606 $aAnimal Genetics and Genomics$3https://scigraph.springernature.com/ontologies/product-market-codes/L32030 606 $aMicrobial Genetics and Genomics$3https://scigraph.springernature.com/ontologies/product-market-codes/L32010 615 0$aPlant breeding. 615 0$aAnimal genetics. 615 0$aMicrobial genetics. 615 0$aMicrobial genomics. 615 14$aPlant Breeding/Biotechnology. 615 24$aAnimal Genetics and Genomics. 615 24$aMicrobial Genetics and Genomics. 676 $a570 676 $a579.135 676 $a591.35 676 $a631.52 676 $a660.6 702 $aLi$b Xiu-Qing$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aDonnelly$b Danielle J$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aJensen$b Thomas G$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298292803321 996 $aSomatic Genome Manipulation$92503138 997 $aUNINA